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Management of Cushing's disease using cavernous sinus sampling: effectiveness in tumor lateralization |
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| Authors: | Gazioglu Nurperi Ulu Mustafa Onur Ozlen Fatma Albayram Sait Islak Civan Kocer Naci Oz Buge Tanriover Necmettin Yetkin Demet Ozgil Gundogdu Sadi Acbay Ozer Kadioglu Pinar |
| Institution: | Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey. nurperi@istanbul.edu.tr |
| Abstract: | OBJECTIVE: The aim of this study was to determine the accuracy of bilateral cavernous sinus sampling (CSS) in preoperative tumor lateralization (right/left) within the pituitary in patients with Cushing's disease (CD). PATIENTS AND METHODS: The study consisted of 26 consecutive patients who had undergone CSS followed by transsphenoidal surgery (TS) for CD between 2000 and 2006 at our institution. The magnetic resonance imaging (MRI) of the selected patients either revealed a normal pituitary or a lesion |
| Keywords: | Adrenocorticotropic hormone Cavernous sinus sampling Cushing's disease MRI Pituitary tumor Surgery Venous sampling |
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