Changes in the peripheral eosinophil count in patients with acute eosinophilic myocarditis |
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Authors: | Shin-ichiro Morimoto Natsuko Kubo Shinya Hiramitsu Akihisa Uemura Masatsugu Ohtsuki Shigeru Kato Yasuchika Kato Atsushi Sugiura Kenji Miyagishima Nami Mori Yukihiko Yoshida Hitoshi Hishida |
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Affiliation: | (1) Division of Cardiology, Department of Internal Medicine, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan;(2) Cardiovascular Center, Nagoya Dai-ni Red Cross Hospital, Nagoya, Japan |
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Abstract: | In many cases, the diagnosis of eosinophilic myocarditis is suggested by an elevated peripheral blood eosinophil count. However, no detailed studies have been performed on the sequential changes in the initial peripheral blood eosinophil count over the course of the disease. We measured the peripheral blood eosinophil count at the time of presentation in eight patients with eosinophilic myocarditis proven by endomyocardial biopsy and intermittently thereafter. The eosinophil count at the time of onset was 500/mm3 in four patients, 500/mm3 but 1000/mm3 in three patients, and 1000/mm3 in one patient. In three of the four patients with an initial eosinophil count of 500/mm3, an increase to 500/mm3 occurred 7–12 days after the onset. The remaining patient did not develop peripheral eosinophilia. In conclusion, in the early stage of eosinophilic myocarditis, peripheral hypereosinophilia is not present initially in some patients, and may not develop during the course of the illness in a subset of these patients. |
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Keywords: | Eosinophil Myocarditis Endomyocardial biopsy |
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