| 仙仲注射液对兔早期膝骨性关节炎血清及软骨中SOD，NO含量的影响 |
| |
| 引用本文： | 王宇强,王小华,杨富国,刘天盛,刘德玉. 仙仲注射液对兔早期膝骨性关节炎血清及软骨中SOD，NO含量的影响[J]. 医学争鸣, 2009, 30(12): 1110-1112 |
| |
| 作者姓名： | 王宇强 王小华 杨富国 刘天盛 刘德玉 |
| |
| 作者单位： | 王宇强,王小华,刘天盛,WANG Yu-Qiang,WANG Xiao-Hua,LIU Tian-Sheng(武警医学院附属医院骨科,天津,300162);杨富国,刘德玉,YANG Fu-Guo,LIU De-Yu(陕西中医学院附属医院骨科,陕西,咸阳,712083) |
| |
| 摘 要： | 目的：评价仙仲注射液对兔早期膝骨性关节炎（OA）血清及软骨中超氧化物岐化酶（SOD）、一氧化氮（NO）含量的影响．方法：120只日本大耳白兔随机分为空白组、模型组（生理盐水每1wk0．5mL，1次）、海诺特组（海诺特每1wk0．5mL，1次）、仙仲Ⅰ，Ⅱ组（仙仲注射液每次0．5mL，每1wk1次和2次），均为关节腔给药．给药8wk后检测血清及关节软骨中SOD，NO含量．结果：仙仲Ⅰ，Ⅱ组及海诺特组与模型组相比，血清及关节软骨中SOD含量均升高（P〈0．01）、NO含量均降低（P〈0．01）．结论：仙仲注射液对早期膝OA关节退变具有一定修护作用．
|
| 关 键 词： | 膝骨性关节炎 仙仲注射液 超氧化物岐化酶 一氧化氮 |
Effect of Xianzhong Injection on superoxide dismutase and nitric oxide in serum and cartilage of rabbits with early stage osteoarthritis |
| |
| WANG Yu-Qiang,WANG Xiao-Hua,YANG Fu-Guo,LIU Tian-Sheng,LIU De-Yu. Effect of Xianzhong Injection on superoxide dismutase and nitric oxide in serum and cartilage of rabbits with early stage osteoarthritis[J]. Negative, 2009, 30(12): 1110-1112 |
| |
| Authors: | WANG Yu-Qiang WANG Xiao-Hua YANG Fu-Guo LIU Tian-Sheng LIU De-Yu |
| |
| Affiliation: | WANG Yu-Qiang1,WANG Xiao-Hua1,YANG Fu-Guo2,LIU Tian-Sheng1,LIU De-Yu2 1Department of Orthopedics,Affiliated Hospital,Medical College,Chinese People's Armed Police Forces,Tianjin 300162,China,2Department of Orthopedics,Shaanxi College of Traditional Chinese Medicine,Xianyang 712083 |
| |
| Abstract: | AIM: To investigate the effect of Xianzhong Injection(XI) on superoxide dismutase(SOD) and nitric oxide(NO) in serum and cartilage of rabbits with early stage osteoarthritis(OA).METHODS: One hundred and twenty rabbits were randomly divided into 5 groups and were given intra-articular injection: the blank group,the model group treated with 0.5 mL normal saline once a week,the positive control group treated with 0.5 mL hyaluronate once a week,and the XI group A and XI group B,treated with 0.5 mL XI respective... |
| |
| Keywords: | knee osteoartritis xianzhong Injection superoxide dismutase nitric oxide |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
