| 几种离子与人类精子顶体反应的关系 |
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| 引用本文： | 王春年,谢文英,徐胜,王一飞.几种离子与人类精子顶体反应的关系[J].中国男科学杂志,1992(3). |
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| 作者姓名： | 王春年 谢文英 徐胜 王一飞 |
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| 作者单位： | 上海第二医科大学组胚教研室，上海第二医科大学组胚教研室，上海第二医科大学组胚教研室，上海第二医科大学组胚教研室 |
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| 摘 要： | 本文用离子载体A23187诱导人类精子的顶体反应,并通过去除介质中Na~+,或在介质中加入K~+阻滞剂,或Ca~(2+)阻滞剂,或Na~+-K~+-ATP酶阻滞剂的方式来研究人类精了顶体反应与几种离子及Na~+泵的关系。结果表明:在人类精子顶体反应时,要有Na~+,K~+,Ca~(++)及Na~+泵的参与。但是,Ca~(++)进入精子的途径可能不是Ca~(++)的通道,
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| 关 键 词： | 离子载体 顶体反应 离子 |
THE RELATIONSHIP BETWEEN SOME IONS AND ACROSOME REACTION OF HUMAN SPERM |
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| WANG Chun-Nian,XIE Wen-Ying,XU Sheng and WANG yi-Fei.THE RELATIONSHIP BETWEEN SOME IONS AND ACROSOME REACTION OF HUMAN SPERM[J].Chinese Journal of Andrology,1992(3). |
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| Authors: | WANG Chun-Nian XIE Wen-Ying XU Sheng and WANG yi-Fei |
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| Institution: | WANG Chun-Nian,XIE Wen-Ying,XU Sheng and WANG yi-Fei Department of Histology and Embryology,Shanghai Second Medical University |
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| Abstract: | Calcium ionophore A 23187 has been used to induce acrosome reaction of human sperm and to investigate the relationship between some ions and acrosome reaction by removing Na~+ from the medium; by adding antagonist of K~+, TEA chloride; or antagonist of Ca~(++), Verapamil; or antagonist of Na~+-K~+-ATPase, acetyl stropharthidin. We have found that in acrosome reaction of human sperm, Na~+, K~+, Ca~(++) and Na~+-K~+-ATPase are required, and the rate of acrosome reaction can been enhanced by adding the antagonist of Ca~(++) (Verapamil). It seems that Ca~(++) ions are not entered by Ca~(++) channels. |
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| Keywords: | acrosome reaction ion ionophore A 23187 |
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