Stent-based delivery of triptolide reduces neointimal formation in rabbit iliac arteries |
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摘 要: | Thelong termclinicalefficacyofintracoronarstentingislimitedbyrestenosis, whichoccursi15% to30% ofpatients 1 In stentrestenosisissolelduetoneointimalhyperplasia Stent baseddeliveryosirolimus, whichinhibitsintimalproliferationbyblockintheG1 /Stransition, hasbeensuccessfullyusedtpreventin stentrestenosisinclinicalpractice PrevioustudieshaveshownthattriptolideinhibitedtheDNAsynthesisofvascularsmoothmusclecellsbyblockingthtransitionfromG0 /G1 toSphase,2 suggestingthatriptolidecouldbeusefulfor…
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关 键 词: | triptolide stents restenosis |
Stent-based delivery of triptolide reduces neointimal formation in rabbit iliac arteries |
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Abstract: | |
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Keywords: | triptolide stents restenosis |
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