静脉用免疫球蛋白和复方甘草酸苷治疗小儿腹型过敏性紫癜疗效比较

目的:评价静脉用免疫球蛋白(IVIG)或复方甘草酸苷(GL)对常规治疗无效的小儿腹型过敏性紫癜(AHSP)的效果。方法:选取我院2013 年1 月至2016 年1 月收治的常规治疗7 d 无缓解的55 例以剧烈腹痛为主要表现的AHSP 患儿,随机分为观察组29 例和对照组26 例。观察组给予IVIG;对照组患儿给予GL,观察治疗前后两组患儿临床症状变化情况。结果:治疗后,观察组患儿紫癜、腹痛恢复时间与对照组比较差异均无统计学意义(P>0. 05)。结论:IVIG 和GL 治疗小儿AHSP 均疗效显著,值得在临床推广应用。

Comparison of Intravenous Immunoglobulin and Compound Glycyrrhizin in the Treatment of Childrenwith Abdominal Henoch Schonlein Purpura

Objective: To evaluate the efficacy of intravenous immunoglobulin (IVIG) or compound glycyrrhizin (GL) in the treatment ofabdominal Henoch Schonlein purpura (AHSP). Methods:Fifty-five AHSP children with abdominal pain as the main manifestation wererandomly divided into two groups: the observation group (n=29) and the control group (n=26). Two groups were treated with routinetreatment for 7 days without any relief from January 2013 to January 2016. The observation group was treated with IVIG, the control groupwas treated with GL, and the clinical symptoms were observed before and after treatment. Results:After treatment, the recovery time ofpurpura and abdominal pain in the observation group had no significant difference, compared with the control group (P>0. 05).Conclusion:IVIG or GL is effective in the treatment of children''s AHSP, and it is worthy to be popularized in clinical practice.