成人甲状腺功能减退在咽喉部的表现分析

摘要：目的探讨成人甲状腺功能减退的程度与其咽喉部表现的关系并预测甲状腺功能减退可能发生的临床表现及其应用价值。方法将50例甲状腺减退分为两组，有咽喉部症状者为甲组（27例）;无咽喉部症状者为乙组（23例）。均行纤维喉镜检查和血清甲状腺激素测定。资料数据应用SPSS18.0统计软件包进行分析，采用χ2检验和t检验。结果50例甲状腺功能减退患者中，出现黏液性水肿面容者甲组21例（77.8%），乙组6例（39.1%）（P=0.005);出现消化道症状者甲组16例（59.3%），乙组6例（26.1%）（P=0.025);出现心悸、气短者甲乙两组分别为5例（18.5%）和4例（17.4%）（P=0.900);出现乏力、精神差、嗜睡者甲乙两组分别为11例（40.7%）和9例（39.1%）（P=0.900)。血清甲状腺激素均有一定程度异常，甲乙两组FT3均数分别是=1.38和=1.45（P＜0.05），FT4均数分别是=0.39和=0.45（P＜0.001），TSH均数分别是=58.79和=53.35（P＜0.05），A Tpo均数分别是=162.44和=41.35（P＜0.001）。结论甲状腺激素水平越低越易出现咽喉部症状。甲状腺功能减退是引起咽喉部疾病病因之一，血清甲状腺激素测定在咽喉部疾病中是一种有效的病因学诊断方法。

Clinical analysis of throat symptoms in adult hypothyroidism

Abstract:ObjectiveTo investigate the relationship between the degree of hypothyroidism and the symptoms of the throat in adults, and to predict the possible clinical manifestations of hypothyroidism and their applications.Methods50 patients suffering from hypothyroidism were divided into two groups, those with throat symptoms were partitioned into group A and those without throat symptoms into group B. All patients in both groups underwent fiber laryngoscopy and thyroid hormone determination. Chi square test and t test with SPSS 18.0 software were used in data analyses.ResultsThe occurrence rates of myxedema face in group A and B were 77% and 39.1% respectively (P=0.005). The incidences of gastrointestinal symptoms were 59.3% and 26.1% in group A and B (P=0.025), while those of palpitations, shortness of breath were 18.5% and 17.4% (P=0.900) respectively. Abnormalities of serum thyroid hormones to certain extent were founded in both groups. The average values of FT3 in group A and B were 1.38 and 1.45 respectively (P<0.001), while those of FT4 were 0.39 and 0.45(P<0.001), TSH were 58.79 and 53.35 and those of A Tpo were 162.44 and 41.35(P<0.001).ConclusionIn patients with hypothyroidism, the lower the thyroid hormone levels are, the more likely throat symptoms are developed. Hypothyroidism is one of the causes of throat diseases, and serum thyroid hormone determination is effective for the etiological diagnosis of throat diseases.