影响变应性鼻炎发病及预后的相关 危险因素Logistic回归分析

目的探讨影响变应性鼻炎发病及预后的相关危险因素，为预防变应性鼻炎的发病提供科学依据。方法选取我科190例变应性鼻炎患者和190例健康志愿者为研究对象，应用Logistic多元回归来探讨变应性鼻炎发病及预后相关危险因素。结果单因素、多因素分析均显示家族史、尘螨过敏、吸烟史、花粉过敏、被褥晾晒、开放空调、开窗通风、饲养宠物、食物过敏等同变应性鼻炎关系密切（P<0.05），且其治疗总有效率为87.3%；预后同性别呈相关性（P<0.05），同家族史、并发症、过敏原数量、有无过敏史、治疗时间及针数等无关（P>0.05）。结论家族史、尘螨过敏、吸烟史、花粉过敏、饲养宠物、食物过敏等因素为变应性鼻炎的危险因素，被褥晾晒、开放空调及开窗通风则是其保护因素；性别对其预后有一定影响。临床应该提高重视并采取针对性措施对其进行干预。

Logistic regression analysis of risk factors affecting the incidence and prognosis of allergic rhinitis

ObjectiveTo explore the risk factors affecting the incidence and prognosis of allergic rhinitis (AR) and provide scientific basis for the prevention of this disease.Methods190 patients suffering from AR and 190 healthy volunteers were enrolled in this study, and logistic multiple regression was adopted to explore the factors affecting the incidence and prognosis of AR.ResultsBoth univariate and multivariate analyses showed that family history, dust mite allergy, history of smoking, pollen allergy, bedding drying, open air conditioning, room ventilation, pets feeding, food allergy had equivalently close relationship with AR (all P<0.05). And the total therapeutic effect was 87.3%. Analyses also showed that the prognosis was correlated to the gender of patients (P<0.05), and not to family history, complications, number of allergens, history of allergy, treatment time and pin numbers (all P>0.05).ConclusionsFamily history, dust mite allergy, smoking history, pollen allergy, pets feeding, food allergy and so on are risk factors for AR, and air basks in bedding, air conditioning opening and room ventilation are the protective factors. The gender of patient has certain influence on the prognosis of AR. In clinical practice, we need to raise awareness on AR and pertinence measures should be taken for intervention.