Mucoepidermoid Carcinoma Arising in a Background of Sialadenoma Papilliferum: A Case Report |
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Authors: | Wei Liu Douglas R Gnepp Egbert de Vries Haidy Bibawy Marshall Solomon Elizabeth S Gloster |
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Institution: | (1) Departments of Pathology, SUNY Downstate Medical Center, 450, Clarkson Avenue, Brooklyn, NY 11203, USA;(2) Department of Pathology, Albert School of Medicine at Brown University, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA;(3) Department of Otolaryngology, SUNY Downstate Medical Center, 450, Clarkson Avenue, Brooklyn, NY 11203, USA |
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Abstract: | Sialadenoma papilliferum is a rare tumor, primarily of minor salivary gland origin, first described by Abrams and Finck (Cancer
24:1057–63, 1969). It is both an exophytic and endophytic papillary lesion histologically resembling syringocystadenoma papilliferum of sweat
gland. The tumor is considered benign although rare recurrent cases have been reported. Three cases of malignant transformation
of sialadenoma papilliferum have been described in the literature. We report a high grade mucoepidermoid carcinoma arising
in a background of sialadenoma papilliferum, at the base of the tongue, an unusual location for minor salivary gland neoplasms.
Eleven months after excision and nodal dissection, there is no evidence of recurrence or metastasis. |
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Keywords: | Sialadenoma papilliferum Mucoepidermoid carcinoma Salivary gland |
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