Discriminant functions in differential diagnosis of hypercalcemic patients |
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Authors: | J A Gibb S A Ogston C R Paterson J R Evans |
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Affiliation: | Department of Biochemical Medicine, Stracathro Hospital, Angus, Scotland, U.K. |
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Abstract: | Using readily available biochemical assays of plasma and urine constituents, we have defined discriminant functions useful as a guide to the differential diagnosis of patients with hypercalcemia. The decreasing rank order of contribution of the variables to the discriminant functions was as follows: plasma albumin, plasma phosphate, plasma chloride, log10 (calcium excretion per liter of glomerular filtrate), and log10 (plasma gamma-glutamyltransferase). Discriminant functions have been defined for patients with values for plasma creatinine above and below 185 mumol/L, and for practical conditions in which plasma and urine samples, or plasma samples only, are available. |
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