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Synthesis and evaluation of cytotoxicity of stilbene analogues
Authors:Sang?Kook?Lee  author-information"  >  author-information__contact u-icon-before"  >  mailto:sklee@ewha.ac.kr"   title="  sklee@ewha.ac.kr"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Kyung?Ae?Nam,Yeon?Hoi?Hoe,Hye-Young?Min,Eun-Young?Kim,Hyojin?Ko,Soyoung?Song,Taeho?Lee,Sanghee?Kim
Affiliation:College of Pharmacy, Ewha Womans University, 11-1 Daehyun-dong, Seodaemun-ku, Seoul 120-750, Korea. sklee@ewha.ac.kr
Abstract:Resveratrol analogs were newly synthesized and evaluated for cytotoxicity in cultured human lung and colon cancer cells. 3,5,4-Trimethoxy-trans-stilbene and 3,5,2',4'-tetramethoxy-trans-stilbene were found to be more potent rather than resveratrol. 3,4,5-Trimethoxy-4'-bromo-cis-stilbene was the most active among the test compounds.
Keywords:Cytotoxicty  Stilbene analogues  Resveratrol analogues
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