| 全身麻醉药镇痛作用受体机制的研究进展 |
| |
| 引用本文： | 闫肃,戴体俊,程伟. 全身麻醉药镇痛作用受体机制的研究进展[J]. 中国药理学通报, 2008, 24(10) |
| |
| 作者姓名： | 闫肃 戴体俊 程伟 |
| |
| 作者单位： | 1. 徐州医学院麻醉学院,江苏,徐州,221002
2. 徐州医学院麻醉药理学教研室,江苏,徐州,221002 |
| |
| 基金项目： | 国家自然科学基金，江苏省自然科学基金 |
| |
| 摘 要： | 镇痛作用是全身麻醉药最重要的药理作用。全身麻醉药镇痛作用的机制较为复杂,可能与GABAA受体、NMDA受体、甘氨酸受体、阿片受体和神经元烟碱受体等有关,此外还可能涉及其它机制,包括非特异性机制。现就全身麻醉药镇痛作用与受体的关系作一综述。
|
| 关 键 词： | 全身麻醉药 镇痛 受体 机制 |
Research progress on receptor mechanisms of analgesia of general anesthetics |
| |
| YAN Su,DAI Ti-jun,CHENG Wei. Research progress on receptor mechanisms of analgesia of general anesthetics[J]. Chinese Pharmacological Bulletin, 2008, 24(10) |
| |
| Authors: | YAN Su DAI Ti-jun CHENG Wei |
| |
| Affiliation: | YAN Su1,DAI Ti-jun2,CHENG Wei1(1. Institute of Anesthesiology,2. Dept of Anaesthetic Pharmacology,Xuzhou Medical College,Xuzhou Jiangsu 221002,China) |
| |
| Abstract: | Analgesic effect is the most important pharmacologic action of general anesthetics.The receptor mechanisms of analgesia of general anesthetics are complex,which may be related to GABAA receptor,NMDA receptor,glycine receptor,opioid receptor,nnAChRs and so on.In addition,other non-specificity mechanisms may also be involved.In this paper,the receptor mechanisms of analgesia of general anesthetics are reviewed. |
| |
| Keywords: | general anesthetics analgesia receptor mechanism |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
