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Hepatic expression of multiple acute phase proteins and down-regulation of nuclear receptors after acute endotoxin exposure
Authors:Fang Che  Yoon Seokjoo  Tindberg Niclas  Järveläinen Harri A  Lindros Kai O  Ingelman-Sundberg Magnus
Affiliation:Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm 17177, Sweden.
Abstract:
Keywords:APP, acute-phase proteins   APR, acute-phase response   LPS, lipopolysaccharide   LBP, LPS-binding protein   TLR, Toll-like receptor   I-κBα, inhibitory protein-κBα   CDK4, cyclin-dependent kinase 4   GST, glutathione S-transferase   LACS, long chain acyl-CoA synthetase   SCYA, small inducible cytokine A3 precursor   GPX, glutathione peroxidase   PLA2, phospholipase A2   RXR, retinoic X receptor   CAR, constitutive androstane receptor   PXR, pregnane X receptor   PPAR, peroxisome proliferator-activated receptor   FXR, farnesoid X receptor   LXR, liver X receptor
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