| 不同厂家维C银翘片质量比较研究及问题分析 |
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| 引用本文： | 张伟南 相雨,江嫄嫄,李卓明,张志华,张花,李砺.不同厂家维C银翘片质量比较研究及问题分析[J].中国中药杂志,2007,32(22):2364-2367. |
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| 作者姓名： | 张伟南 相雨 江嫄嫄 李卓明 张志华 张花 李砺 |
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| 作者单位： | 佛山德众药业有限公司,广东,佛山,528000 |
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| 摘 要： | 目的：研究不同厂家维C银翘片的质量情况以及对问题的分析,为提高药品标准,正确地评价药品质量提供理论依据。方法：通过对11家厂家18批样品进行片芯重量测定,样品粉末显微镜观察,维生素C含量测定,以及建立维C银翘片中绿原酸的HPLC含量测定方法和建立维C银翘片中牛蒡子苷的HPLC含量测定方法,并对样品中绿原酸和牛蒡子苷的含量进行测定比较。结果：不同厂家的产品,显微观察及各种测定结果均存在很大差异。结论：由于各厂家生产情况不同,同一产品的质量存在较大差别。
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| 关 键 词： | 维C银翘片 质量研究 维生素C |
| 文章编号： | 1001-5302（2007）22-2364-04 |
| 收稿时间： | 2006-01-29 |
| 修稿时间： | 2006年1月29日 |
A comparative research on quality of Vitmin C Yinqiao tablets from different manufacturers |
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| ZHANG Wei-nan; XIANG Yu; JIANG Yuan-yuan; LI Zhuo-ming; ZHANG Zhi-hua; ZHANG Hua; LI Li.A comparative research on quality of Vitmin C Yinqiao tablets from different manufacturers[J].China Journal of Chinese Materia Medica,2007,32(22):2364-2367. |
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| Authors: | ZHANG Wei-nan; XIANG Yu; JIANG Yuan-yuan; LI Zhuo-ming; ZHANG Zhi-hua; ZHANG Hua; LI Li |
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| Institution: | Foshan Dezhong Phamaceutical Co. Ltd. , Foshan 528000, China |
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| Abstract: | Objective: To study the different manufacturers Vitmin C(Vc) Yinqiao tablets,and the quality of the analysis of the problem,to provide a theoretical basis for the correct evaluation of the quality of medicines and improving the standard drugs.Method: 11 manufacturers of 18 batches of samples for determination of the weight of the core tablets,powder samples were observed with microscope,determination of Vc,and the establishment of the VC!yinqiao tablets HPLC method for determination of chlorogenic acid and arctigenin,chlorogenic acid and arctigenin in the samples were measured and compared.Result: There is a big difference of microscope and various measured results in different manufacturers products.Conclusion: Because different manufacturers to produce the same,there are big differences in the quality of the products. |
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| Keywords: | VC Yinqiao tablet quality research vitamin C |
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