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体外循环搏动灌注对肾功能不全患者的影响
引用本文:叶兴宏. 体外循环搏动灌注对肾功能不全患者的影响[J]. 中国医师杂志, 2011, 0(Z1)
作者姓名:叶兴宏
作者单位:杭州市萧山第一人民医院麻醉科,杭州,311201
摘    要:目的 评价体外循环搏动灌注对肾功能不全患者的影响.方法 2007年1月至2010年5月共收治肾功能不全患者55例行心脏直视手术,随机分为搏动灌注组(P组)28例与非搏动灌注组(NP组)27例.分别检测两组患者术前及术后24 h尿素氮、肌酐、尿酸、术中单位时间尿量.主动脉开放前进行血气、电解质分析及乳酸测定.结果 主动脉开放前P组乳酸值明显低于NP组(P<0.01),手术前后尿酸差值P组明显高于NP组(P<0.01),术中单位时间尿量P组明显多于NP组(P<0.01).结论 与非搏动灌注相比,体外循坏采用搏动灌注有利于肾功能不全患者的肾保护.

关 键 词:搏动灌注  肾功能不全

The effects of pulsatile perfusion during cardiopulmonary bypass procedures on renal inadequacy
YE Xing-hong. The effects of pulsatile perfusion during cardiopulmonary bypass procedures on renal inadequacy[J]. Journal of Chinese Physician, 2011, 0(Z1)
Authors:YE Xing-hong
Abstract:Objective To evaluate the clinical effects of pulsatile perfusion on the renal inadequacy during cardiopulmonary bypass ( CPB). Methods From January 2007 to May 2010, 55 patients with renal inadequacy undergoing open heart surgery were randomized into pulsatile group ( n = 28 ) and nonpulsatile group (n =27). Following parameters were examined: urea nitrogen , creatinine,uric acid, urine volume and blood gas, electrolyte and lactic acid before arteriae aorta opening. Results The urine volume during CPB was significant higher in the pulsatile group ( P <0. 01). The blood lactate level before arteriae aorta opening were significant lower in the pulsatile group ( P <0. 01). Conclusion The pulsatile flow is better than nopulsatile flow in oxygen metabolism of renal protection.
Keywords:Pulsatile perfusion  Renal inadequacy
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