| 从高原急进特高海拔地区人体血浆内皮素—1水平的变化及其意义 |
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| 引用本文： | 薛增军,李英悦.从高原急进特高海拔地区人体血浆内皮素—1水平的变化及其意义[J].高原医学杂志,1997,7(4):23-24. |
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| 作者姓名： | 薛增军 李英悦 |
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| 作者单位： | 西藏军区总医院全军高山病防治中心，西藏军区总医院全军高山病防治中心，西藏军区总医院全军高山病防治中心，西藏军区总医院全军高山病防治中心 |
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| 摘 要： | 目的：为探讨ＥＴ－１在高原地区及急进特高海拔地区的变化及其对急慢性高原病的意义；方法：Ｃ地２０名健康战士在主原和急进特高海拔后的血浆ＥＴ－１水平进行检测，同时检测了两地的血氧饱和度；结果Ｌ：高原地区的ＥＴ－１水平明显高于平原参考值，急进海拔４７００ｍ后ＥＦ－１水平更显著的增高，且与ＳａＯ２呈明显负要关。结论：在高原地区及急进特高海拔后ＥＴ－１水平皆增同，ＦＴ－１水平的增高是生高原病发病的重要因素。
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| 关 键 词： | 高原 急性缺氧 内皮素－1 环境生理 病理 |
PLASMA LEVELS OF ET-1 IN SUBJECTS ACUTE EXPOSED TO EXTREME ALTITUDE FROM 3 658m ALTITUDE |
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| Xue Zhengjun.PLASMA LEVELS OF ET-1 IN SUBJECTS ACUTE EXPOSED TO EXTREME ALTITUDE FROM 3 658m ALTITUDE[J].Journal of High Altitude Medicine,1997,7(4):23-24. |
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| Authors: | Xue Zhengjun |
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| Institution: | The General Hospital of Tibet Millitary Command |
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| Abstract: | To study ET-1 levels at high altitude of 3 658m and 4 700m. Methods:ET-1 and SaO2 were measured with radioimmunoassary in 20 healthy young objects. Results:ET-1 level at hing altitude of 3 658m was significantly higher than in plain (P<0. 05)and significantly increased in 4 700m(p<0. 01). The SaO2 at 4 700m decreased significantly than that at 3 658m(P< 0. 01 ). Conclusions: There was a negative correlation between SaO2 and ET-1 level (P<0. 01,r=0. 638). The ET-1 could play an important role in formation of AMS and CMS. |
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| Keywords: | High altitude Endothelin-1 |
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