诊断性玻璃体手术临床应用及其微创化前景

诊断性玻璃体手术是对一些病因不明、治疗无效的眼内炎性疾病或恶性肿瘤等进行玻璃体手术,从而获得玻璃体和视网膜或脉络膜标本,再运用现代分子生物学技术和实验室技术进行明确诊断的一种手段.诊断性玻璃体手术可以明显提高临床医师对原因不明和传统方法治疗无效的非典型葡萄膜炎,可疑感染的眼内炎,进行性视网膜、脉络膜及色素上皮病变,伪装综合征及疑为恶性肿瘤的眼内出血的诊断率,可用于治疗慢性葡萄膜炎的并发症.诊断性玻璃体手术的微创化发展使手术更方便、更快捷、更安全.

Clinical application of diagnostic vitrectomy and prospective microincision techniques

Diagnostic vitrectomy is a procedure that can obtain vitreous, retina or choroid specimens form patients with intraocular inflammation or malignant tumors with obscured etiology or ineffective treatment by performing vitrectomy. Then, an accurate diagnosis could be obtained from these specimens by using molecular biological techniques. Diagnostic vitrectomy procedure can be applied for improving diagnosis of atypical uveitis with unknown causes, atypical infectious endophthalmitis, progressive retinitis/choroiditis and retinal pigment epithelium diseases, masquerade syndrome, intraocular bleeding with suspected malignant origin and also can be used for the treatment of complication of chronic uveitis. Microincision diagnostic vitrectomy is a convenient, rapid and safe procedure developed from regular diagnostic vitrectomy.