| 金铁锁化学成分及抑菌活性研究 |
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| 引用本文： | 王垄,龚小见,周欣,先春,杨世林,杨占南.金铁锁化学成分及抑菌活性研究[J].中国中药杂志,2012,37(23):3577-3580. |
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| 作者姓名： | 王垄 龚小见 周欣 先春 杨世林 杨占南 |
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| 作者单位： | 1. 贵州师范大学天然药物质量控制研究中心,贵州贵阳550001;贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室,贵州贵阳550001
2. 贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室,贵州贵阳,550001 |
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| 基金项目： | 贵州省中药现代化科技产业研究开发专项项目;贵州省科技创新人才团队建设项目;贵阳市科学技术计划项目 |
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| 摘 要： | 目的:研究金铁锁的化学成分及抑菌活性.方法:采用硅胶柱色谱、凝胶柱色谱等手段进行分离、纯化,根据波谱数据和理化性质进行结构鉴定.结果:从金铁锁的乙醇提取物中分离得到10个单体化合物,分别为对羟基苯甲酸甲酯(1),N-甲基糖精(2),3-羟基--4-甲氧基苯甲酸(3),日尔曼醇(4),二十三烷酸(5),二十八烷(6),杜鹃花酸(7),琥珀酸(8),stellarine A(9),齐墩果烷-12-烯-3α,16α-二羟基-23,28-二酸(10).结论:除化合物10之外,其他化合物均为首次从金铁锁属植物中分离得到.研究表明化合物8,9有一定的抑菌活性.
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| 关 键 词： | 金铁锁 化学成分 抑菌活性 |
| 收稿时间： | 2012/7/27 0:00:00 |
Chemical constituents of Psammosilene tunicoides and bacteriostatic activity |
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| WANG Long,GONG Xiao-jian,ZHOU Xin,XIAN Chun,YANG Shi-lin and YANG Zhan-nan.Chemical constituents of Psammosilene tunicoides and bacteriostatic activity[J].China Journal of Chinese Materia Medica,2012,37(23):3577-3580. |
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| Authors: | WANG Long GONG Xiao-jian ZHOU Xin XIAN Chun YANG Shi-lin and YANG Zhan-nan |
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| Institution: | Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China;School of Chemistry and Material Science, Guizhou Normal University, Guiyang 550001, China |
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| Abstract: | |
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| Keywords: | Psammosilene tunicoides chemical constituent bacteriostatic activity |
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