| 西洛他唑微粉化片剂的制备和溶出度测定 |
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| 引用本文： | 徐成,周勤,丁峰.西洛他唑微粉化片剂的制备和溶出度测定[J].药学与临床研究,2006,14(6):360-362. |
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| 作者姓名： | 徐成 周勤 丁峰 |
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| 作者单位： | 江苏吴中苏药医药开发有限责任公司,南京210009 |
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| 摘 要： | 目的 研究提高西洛他唑溶出度的方法。方法 使用球磨机制备西洛他唑微粉化混合物，并以此添加适合的辅料制备片剂。结果 经测定制剂的溶出度达到《中国药典》要求。初步稳定性试验，结果表明本品稳定。结论 该制备方法简单可行，溶出度合格。
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| 关 键 词： | 微粉化 西洛他唑 溶出度 |
| 文章编号： | 1007-306（2006）06-360-03 |
| 收稿时间： | 2006-07-03 |
Studies on the prepatation and dissolution of micronized cilostazol tablets |
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| XU Chen,ZHOU Qin and DING Feng.Studies on the prepatation and dissolution of micronized cilostazol tablets[J].Pharmacertical and Clinical Research,2006,14(6):360-362. |
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| Authors: | XU Chen ZHOU Qin and DING Feng |
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| Abstract: | AIM To improve the dissolution of cilostazol tablet. METHODS The micronized cilostazol was prepared by using ball mill. Some suitable adjuvants were used to prepare the micronized cilostazol tablets. RESULTS The disintegration tests suggested that the dissolution of micronized cilostazol tableta conformed to the requirement of Ch. P 2005. The stability of the preparation was studied, and the results showed that the product was stable. CONCLUSION The preparation procedure was simple and feasible. The dissolution of cilostazol was up to the standard. |
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| Keywords: | Micronization Cilostazol Dissolution |
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