新生儿社区获得性肺炎病原菌及药物敏感分析

目的:探讨本地区新生儿社区获得性肺炎常见病原菌分布及耐药情况,为临床经验性使用抗生素提供参考依据。方法:对2010年1月～2012年1月我院新生儿收治的145例社区获得性肺炎,将其痰液的病原菌培养结果及药敏情况进行回顾性分析。结果:145例肺炎患儿均送检痰培养,痰培养阳性率69.65%,其中革兰氏阴性菌(G-)占68.31%,革兰氏阳性菌(G+)占23.7%,病原菌排前五位的为:大肠埃希菌、肺炎克雷伯、金黄色葡萄球菌、鲍曼不动杆菌、阴沟肠杆菌。革兰氏阴性菌对头孢二三代耐药性高,对亚胺培南敏感性高;革兰氏阳性菌对青霉素耐药,对万古霉素及利奈唑胺全部敏感。结论:本地区新生儿社区获得性肺炎病原菌以革兰氏阴性菌为主,以大肠埃希菌、肺炎克雷伯、金黄色葡萄球菌为主要病原菌,对亚胺培南、万古霉素、利奈唑胺全部敏感。

Analysis of Pathogens And Drug Resistance Of Neonatal Community - acquired Pneumonia

Objective:In order to investigate distribution and Drug Resistance for common pathogens of local Neonatal community-acquired pneumonia,and provide reference for clinical using antibiotics empirically.Method:During January 2010 to January 2012,our hospital have analyzed retrospectively 145 cases of community-acquired pneumonia by analyzing the results of sputum culture for pathogens and drug resistance.Result:By cultivating the sputum of 145 cases of community-acquired pneumonia,it proved that positive rate for sputum culture 69.65% ;including Gram-negative bacteria 68.31%,Gram-positive bacteria 23.7%.The most 5 kinds of pathogen in proper order:1.Escherichia coli,2.Pneumonia clay,3.Staphylococcus aureus,4.baumanii,5.Agrobacteria cloacae.In addition,Gram-negative bacteria has most tolerance against 2nd and 3rd generation Cephalosporin.,also has most sensitivity against imipenem.Gram-positive bacteria has tolerance against penicillin and totally has sensitivity against vancomycin & rina thiazole amine.Conclusion:Gram-negative bacteria is the main pathogen of Neonatal Community-acquired Pneumonia,which also inlcludes Escherichia coli,pneumonia clay,It totally has sensitivity against imipenem.