In Vitro Activities of Six New Fluoroquinolones against Brucella melitensis |
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| Authors: | Ignacio Trujillano-Martín Enrique García-Snchez Isaías Montes Martínez María Jos Fresnadillo Jos Elías García-Snchez and Josngel García-Rodríguez |
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| Institution: | Ignacio Trujillano-Martín, Enrique García-Sánchez, Isaías Montes Martínez, María José Fresnadillo, José Elías García-Sánchez, and JoséÁngel García-Rodríguez |
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| Abstract: | We have tested the in vitro activities of eight fluoroquinolones against 160 Brucella melitensis strains. The most active was sitafloxacin (MIC at which 90% of the isolates are inhibited [MIC90], 0.12 μg/ml). In decreasing order, the activities (MIC90s) of the rest of the tested fluoroquinolones were as follows: levofloxacin, 0.5 μg/ml; ciprofloxacin, trovafloxacin, and moxifloxacin, 1 μg/ml; and ofloxacin, grepafloxacin, and gatifloxacin, 2 μg/ml. |
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