骨痨汤治疗脊柱结核的临床应用研究

目的：评价骨痨汤辅助治疗脊柱结核的临床效果，以探讨其临床适用性。方法选择2010年6月~2013年4月于本院就诊的初治型脊柱结核患者60例，采用简单随机数字表法分为治疗组30例和对照组30例，两组患者均采用相同的基础治疗方法，包括全身抗结核治疗及手术治疗，治疗组在此基础上加用骨痨汤随证加减治疗。观察两组患者的临床症状消失时间、血沉及C反应蛋白恢复正常时间、骨性融合时间及治疗后的总疗效。结果治疗组患者治疗后午后潮热、盗汗、局部疼痛等症状消失时间较对照组明显缩短，血沉及C反应蛋白恢复正常时间早于对照组，达到骨性融合时间明显早于对照组，差异均有统计学意义（P＜0.05），治疗组患者的总有效率为90.0%，对照组为66.7%，两组差异有统计学意义（字2=4.8118，P=0.0283）。结论骨痨汤辅助治疗脊柱结核时可以较快地改善患者的临床症状，促进骨骼愈合，适合临床推广应用。

Clinical applications research of Gulao decoction in the treatment of spinal tuberculosis

Objective To analyze the clinical applications of Gulao decoction in the treatment of spinal tuberculosis,in order to explore its clinical applications. Methods 60 cases of spinal tuberculosis from June 2010 to April 2013 in our hospital were used randomly number table and divided into the treatment group of 30 patients and the control group of 30 patients, two patients were used the same basic treatment methods,including systemic anti-TB treatment and surgi-cal treatment,while the treatment group on this basis was given Gulao decoction.The disappearing time of the clinical symptoms,blood CRP becoming normal time,bony fusion time and total efficacy after treatment of two groups were ob-served. Results The disappearing time of afternoon hot flashes,night sweats,local pain and other symptoms in the treat-ment group were significantly shorter than the control group,erythrocyte sedimentation rate and C-reactive protein were earlier than the control group,bony fusion time was significantly earlier than the control group,the differences were sta-tistically significant （P〈0.05）,the therapeutically effective rate of the treatment group was 90.0% in the control group were 66.7%,the difference was statistically significant （χ2=4.8118,P=0.0283）. Conclusion Gulao decoction in the treat-ment of spinal tuberculosis can assist rapid improvement of clinical symptoms,promote bone healing,and is suitable for clinical application.