| ATP-Mg~(2+)对缺血缺氧心肌保护作用的实验研究 |
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| 引用本文： | 杨宗伟,金基焕. ATP-Mg~(2+)对缺血缺氧心肌保护作用的实验研究[J]. 延边医学院学报, 1990, 0(4) |
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| 作者姓名： | 杨宗伟 金基焕 |
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| 作者单位： | 延边医学院附属医院心胸外科，延边医学院附属医院心胸外科 |
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| 摘 要： | 用离体大鼠心脏灌流方法观察了ATP-Mg~(2+)等对缺血缺氧心脏再灌注后心功能的影响及超微结构变化。结果表明,ATP-Mg~(2+)对缺血缺氧心肌具有明显的保护效果,其作用与ATP-MgCl_2几乎相同;两者均优于单纯性ATP(ATP-2Na)。作者认为,ATP-Mg~(2+)是ATP-MgCl_2,心肌保护的有效成分。
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| 关 键 词： | 心肌 灌注法 创伤和损伤 心脏 |
The effect of ATP-Mg~(2+) myocardial ischemia and reperfusions |
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| Yang Zhongwei,Jin Jihuan. The effect of ATP-Mg~(2+) myocardial ischemia and reperfusions[J]. Journal of Medical Science Yanbian University, 1990, 0(4) |
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| Authors: | Yang Zhongwei Jin Jihuan |
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| Abstract: | The effect of ATP-Mg~(2+) on myocardial ischemia and reperfusions was evaluated by isolated rat heart preparations and compared with those of individually administered ATP-Mgcl_2 and ATP. The effect of ATP-Mg~(2+) on cardiac function and ultrastructure after cardiac ischemia repurfusions was observed. The results show that ATP-Mg~(2+) has a significant protective effect on cardiac ischemia reperfusions. The effect is simlliar to ATP-MgCI_2. These effects are both superior to that of ATP-2 Na. It is suggested that the effective element of ATP-MgCl_2 is ATP-Mg~(2+). |
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| Keywords: | myocardium adenosine triophosphate magnesium. |
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