Efficacy and safety of ingenol mebutate gel in field treatment of actinic keratosis on full face,balding scalp,or approximately 250 cm2 on the chest: A phase 3 randomized controlled trial |
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| Affiliation: | 1. Laser and Skin Surgery Center of Indiana, Carmel, Indiana;2. Enverus Medical, Surrey, British Columbia, Canada;3. LEO Pharma A/S, Ballerup, Denmark;4. Veracity Clinical Research, Brisbane, Queensland, Australia;1. Medical Scientist Training Program, Tufts University School of Medicine, Boston, Massachusetts;2. Division of Dermatology, Lahey Hospital and Medical Center, Burlington, Massachusetts;1. Department of Dermatology at Saint Louis University School of Medicine, Missouri;2. Department of Pediatric Dermatology at Cardinal Glennon Hospital at Saint Louis University School of Medicine, Missouri;3. Saint Louis University Center for Outcomes Research, Missouri;1. Department of Dermatology, Mayo Clinic, Rochester, Minnesota;2. Surgical Dermatology Group, Birmingham, Alabama;3. Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota |
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| Abstract: | |
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| Keywords: | actinic keratosis field cancerization field treatment ingenol mebutate 5-FU" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" 5-fluorouracil AE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" adverse event AK" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" actinic keratosis AKCLEAR 100" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" complete clearance of clinically visible AK lesions in the treatment area AKCLEAR 75" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" 75% reduction or greater in the number of clinically visible AK lesions in the treatment area IngMeb" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" ingenol mebutate LSR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" local skin response |
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