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Discovery and Structure-Based Optimization of Adenain Inhibitors
Authors:Aengus Mac Sweeney  Philipp Grosche  David Ellis  Keith Combrink  Paul Erbel  Nicola Hughes  Finton Sirockin  Samu Melkko  Anna Bernardi  Paul Ramage  Nadine Jarousse  Eva Altmann
Affiliation:Novartis Institute for Biomedical Research, Novartis Campus, CH-4002 Basel, Switzerland;Novartis Institute for Biomedical Research, 6201 South Freeway, Fort Worth, Texas 76134-2099, United States;§NovartisInstitute for Biomedical Research, 4560 Horton Street, Emeryville, California 94608-2916, United States
Abstract:
Keywords:Adenoviralprotease   adenoviral infection   inhibitor X-raycocrystal structure   structure-based design
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