Epidemiology of carcinoma of the cervix (author's transl)]

In order to explain why modes of sexual life influence the incidence of cervical carcinoma, several factors have been claimed to be involved. There is no solid basis for the hypothesis that sperm may be mutagenic. By contrast, epidemiological studies showed that partners whose life is not sedentary bring back home to their wives an increased risk of cervical carcinoma. The infectious factor does not seem to be associated with syphilis but may well be represented by herpes genitalis virus (Herpes Simplex type 2 virus). Women with cervical carcinoma show a variety of immunes reactions to this virus, and these reactions are statistically less frequent in control groups. In the laboratory, mouse and hamster cells have been transformed into cancerous cells by means of herpes simplex virus type 2.