Dose-response effects of albuterol aerosol compared with isoproterenol and placebo aerosols: response to albuterol, isoproterenol, and placebo aerosols. |
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Authors: | S L Spector M Garza Gomez |
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Affiliation: | 1. From the Department of Medicine, Section of Allergy and Clinical Immunology, the National Jewish Hospital and Research Center Denver, Colo., U.S.A.;2. Maracaibo, Venezuela |
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Abstract: | Albuterol aerosol was an effective bronchodilator as reflected by indices of pulmonary function obtained from spirometry and flow volume curves; Compared with isoproterenol, there were minimal side effects even at the highest doses, and bronchodilation lasted significantly longer. In addition albuterol was successfully used by a patient with idiopathic hypertrophic subaortic stenosis who was unable to tolerate isoproterenol, as well as by some patients with idiosyncratic responses to isoproterenol; A few patients appeared to derive little benefit from either albuterol or isoproterenol. |
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Keywords: | Reprint requests to: Dr. Sheldon L. Spector 3800 East Colfax Ave. Denver Colo. 80206. |
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