脑肿瘤患者认知功能障碍的初步研究

目的 :探索脑肿瘤患者认知功能障碍的特点。方法 :采用CLB测验对 31例左侧大脑肿瘤患者、34例右侧大脑肿瘤患者及正常对照组进行测验。结果 :(1)左侧大脑脑肿瘤组四项语言—序贯能力测验成绩明显低于对照组 (P <0 .0 5 ) ,四项空间认知能力成绩无明显差别 (P >0 .0 5 ) ,病例组CLQ为正值 ,表明右半球信息加工能力无明显损害 ;(2 )右侧大脑脑肿瘤组四项空间认知能力测验成绩明显低于对照组 (P <0 .0 5 ) ,四项语言—序贯能力测验成绩中系列数字、偏旁组字、类别组词与对照组间无明显差异 (P >0 .0 5 ) ,系列声音测验成绩有明显差异 (P <0 .0 5 ) ,病例组CLQ为负值 ,表明左半球信息加工能力基本正常。结论 :CLB可以对脑肿瘤患者认知功能障碍进行量化 ,是一种评估左右侧大脑肿瘤患者认知功能障碍的有效方法。

Study of Cognitive Function in Cerebral Tumor Patients by Using the Cognitive Laterality Battery

Objective: To examine cognitive functions of the patients with cerebral tumor. Methods: 31 left cerebral hemisphere tumor patients, 34 right cerebral hemisphere tumor patients, and matched healthy controls were assessed on the Cognitive Laterality Battery (CLB). Results: (1) Compared with the control group, results of the left cerebral tumor patients on 4 Sequential-Verbal Abilities were significantly lower ( P <0.05), but there was no significant difference in Visuospatial functioning ( P >0.05).The Cognitive Laterality Quotient(CLQ) of this experimental group was positive, suggesting that the patients' information production abilities of right hemisphere was not impaired.(2)Compared with the control group, results of the right cerebral tumor patients on the 4 Visuospatial Abilities were significantly lower( P <0.05) The test result of serial sounds of the 4 Sequential-Verbal Abilities was also significantly lower than the control group ( P <0.05). The CLQ of this experimental group was negative, suggesting that patients' information production abilities involving the left hemisphere was normal. Conclusion: CLB is a valid test that could be used to assess the cognitive functioning of cerebral tumor patients.