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新辅助放化疗对中晚期食管癌患者疗效的护理观察
引用本文:庄显叶,周运添,包汉康,邹文薏.新辅助放化疗对中晚期食管癌患者疗效的护理观察[J].北方药学,2015(8).
作者姓名:庄显叶  周运添  包汉康  邹文薏
作者单位:1. 广东省惠州市惠东县人民医院 惠东 516300;2. 广东省惠州市惠东县第二人民医院外科 惠东 516351;3. 广东省惠州市中心人民医院放疗科 惠州 516000
摘    要:目的:观察中晚期食管癌患者外科手术前新辅助放化疗的临床护理疗效。方法:试验组136例患者在放疗基础上术前采用2个周期的顺铂加氟尿嘧啶的化疗方案,化疗后2周手术;对照组136例患者无化疗行直接手术。结果:试验组肿瘤明显缩小,其中根治性切除112例,占82.35%;对照组根治性切除89例,占65.44%。两组对比差异显著(P<0.01)。结论:术前新辅助放化疗可降低食管癌肿瘤分期,提高根治性切除手术率,提高术后生存率及生存质量。

关 键 词:中晚期食管癌  新辅助放化疗  手术  生存率

Nursing observation on curative effect of advanced esophageal carcinoma patients with neoadjuvant chemotherapy drugs
Abstract:Objective:To observe the clinical changes of local advanced esophageal carcinoma treated with new adjuvant chemotherapy before operation and subsistence rate of ostoperation.Methods:136 cases with esophageal carcinoma take two periodic chemotherapy before operation. The other 136cases take operation directly.Results:In the test group, the lengths of lesions for 116 cases reduced, and 112 cases were resected entirely (85.35%). In the other group, 89 cases were resected entirely (65.44%). There were significant differences between the two groups (P<0.01).Conclusion:New adjuvant chemotherapy could debase the stage of esophageal carcinoma, increase the resection rate and subsistence rate.
Keywords:Esophageal carcinoma  New adjuvant chemotherapy  Operation  Subsistence rate
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