小青龙汤配合基础治疗对慢性阻塞性肺疾病患者血氧饱和度的影响

目的探讨小青龙汤结合基础治疗对慢性阻塞性肺疾病（COPD）患者血氧饱和度的影响。方法选择COPD急性期患者90例，按照随机数字表法随机分为治疗组和对照组各45例，治疗组患者在抗感染、雾化吸入等基础治疗的同时，每日用小青龙汤1剂水煎服；而对照组仅采用抗感染、雾化吸入等基础治疗。连续治疗2周，以用药前后血气分析的动脉氧分压（PaO2）、动脉二氧化碳分压（PaCO2）评定疗效。结果治疗前两组PaO2、PaCO2无明显差异（P〉0．05）；治疗2周后，两组PaO2明显升高、PaCO2明显降低（P〈0．01）；而治疗组与对照组比较，PaO2升高和PaCO2降低比对照组更明显（P〈0．01）。结论小青龙汤结合基础治疗可达到提高COPD患者血氧饱和度，改善患者缺氧状态的作用。

Effects of Xiaoqinglong decoction combining basic treatment on satuaration of blood oxygen in patient with chronic obstructive pulmonary disease

Objective To explore the effects of Xiaoqinglong decoction （XQLD） combining basic treatment on saturation of blood oxygen in patients with chronic obstructive pulmonary disease（COPD）. Methods 90 cases of patients with acute COPD were chosen and divided into treatment group （n = 45 ） and control group （n = 45 ） according to the method of random digits table. The patients in the treatment group were given the basic treatment such as anti - infection treatment and atomized inhalation, but additional XQLD one dose per day, while the patients in the control group were given basic treatment alone such as anti - infection treatment and atomized inhalation. The treatment continued for two weeks and the efficacy was evaluated in terms of the PaO2 and PaCO2 in blood gas analysis before and after treatment. Results There was no significant difference between two groups in PaO2 and PaCO2 before treatment（ P 〉0.05 ）. After two weeks＇treatment, the PaO2 rose obviously, while PaCO2 obviously fall in both groups（ P 〈0.01 ）. Compared with the control group, the rise of PaO2 and fall of PaCO2 were more significant in the treatment group （ P 〈 0.01 ）. Conclusion Xiaoqinglong decoction combining basic treatment can play a role in improving the saturation of blood oxygen and hypoxia.