持续气道正压通气对老年OSAHS合并2型糖尿病患者胰岛素抵抗的影响 |
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引用本文: | 江宏志,郭冠芬,张平,周柳如. 持续气道正压通气对老年OSAHS合并2型糖尿病患者胰岛素抵抗的影响[J]. 医学临床研究, 2011, 28(3): 493-495 |
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作者姓名: | 江宏志 郭冠芬 张平 周柳如 |
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作者单位: | 广东省东莞市人民医院呼吸内科,广东,东莞,523000 |
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摘 要: | [目的]探讨持续气道正压通气(CPAP)对老年合并2型糖尿病的阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者胰岛素抵抗(IR)的影响.[方法]选择老年合并2型糖尿病的OSAHS患者52例,通过3个月的CPAP治疗,观察治疗前后反映IR的稳态模式评估(HOMA)指数变化.[结果]CPAP治疗3个月后呼吸暂停/低通气指数...
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关 键 词: | 睡眠呼吸暂停综合征/并发症 糖尿病,非胰岛素依赖型/并发症 正压呼吸 |
Effect of Continuous Positive Airway on Insulin Resistance in Elderly Patients with Type 2 Diabetes and OSAHS |
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Affiliation: | JIANG Hong-zhi, GUO Guan-fen, ZHANG Ping,et al ( Department of Respiratory Diseases, the People's Hospital of Dongguan City, Guangdong 523000, China ) |
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Abstract: | [Objective]To explore the effect of continuous positive airway pressure(CPAP) on insulin resist ance(IR) in elderly patients with type 2 diabetes and obstructive sleep apnea hypopnea syndrome(OSAHS). [Methods] Fifty-two elderly patients with type 2 diabetes and OSAHS were enrolled in this study. All patients received CPAP treatment for 3 months. The change of homeostasis model assessment(HOMA) index reflecting IR was observed before and after treatment. [Results] After 3 months of CPAP treatment, the apnea/hypopnea index (AHI) and miniSpO2 were improved significantly compared with that before treatment( P 〈0.01). The HOMA index was significantly decreased after 3 months of CPAP treatment compared with that before treatment(3.62±0.86 vs 1.98±0.78, P 〈0.01). [Conclusion]CPAP treatment can significantly improve the IR in elderly patients with type 2 diabetes and OSAHS. |
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Keywords: | sleep apnea syndromes/CO diabetes mellitus,non-insulin-dependent/CO positive-pressure respiration |
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