| 喉癌组织中核转录因子NF-kB的定量检测 |
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| 引用本文： | 孙余才,胡国华,朱江. 喉癌组织中核转录因子NF-kB的定量检测[J]. 山东医大基础医学院学报, 2007, 0(2) |
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| 作者姓名： | 孙余才 胡国华 朱江 |
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| 作者单位： | 山东济宁医学院附属医院耳鼻喉科 山东济宁272100(孙余才)，重庆医科大学附属第一医院耳鼻喉科 重庆400016(胡国华，朱江) |
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| 摘 要： |
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| 关 键 词： | 喉肿瘤 核转录因子 蛋白质印迹杂交 凝胶电泳迁移率 |
A quantitative analysis of NF-kB in laryngeal carcinoma |
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| SUN Yu-cai,HU Guo-hua,ZHU Jiang. A quantitative analysis of NF-kB in laryngeal carcinoma[J]. Journal of Preclinical Medicine College of Shandong Medical University, 2007, 0(2) |
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| Authors: | SUN Yu-cai HU Guo-hua ZHU Jiang |
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| Affiliation: | SUN Yu-cai1,HU Guo-hua2,ZHU Jiang2 |
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| Abstract: | Objective: To explore the significance of the quantitative analysis of NF-kB in laryngeal carcinoma tissues.Methods: The quantitative analysis of the protein content and the DNA binding activity of NF-kB was examined by the Western blot method and electrophoretic mobility shift assay(EMSA) method in 20 cases of laryngeal carcinoma tissues and 10 cases of normal pericarcinoma tissues.Results: The protein content and the DNA binding activity of NF-kB in laryngeal carcinoma tissues were higher than those in pericarcinoma normal tissues(P<0.05).Conclusion: The NF-kB might play an important role in the occurrence and development of laryngeal carcinoma and offers a new target of laryngeal carcinoma treatment. |
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