康艾配合放射治疗恶性肿瘤57例

目的:研究康艾注射液对恶性肿瘤放射治疗的增敏减毒作用.方法:将110例恶性肿瘤患者随机分成综合组与对照组,行前瞻性研究.两组患者均采用加速器6MW-X线放疗,常规设野,常规分割DT60-70GY,其中宫颈癌患者为外照射加后装照射.综合组在放疗开始即使用康艾注射液,连用40天;对照组单纯放疗.结果:综合组与对照组控制瘤体的完全缓解率分别为66.7%和43.4%;治疗后karnofsky评分改善率为52.6%和32.1%;治疗后白细胞减少发生率为22.8%和41.5%,差异均有显著性意义(P＜0.05).综合组治疗前、后T淋巴细胞亚群差异意义无显著性意义(P＞0.05),对照组治疗前、后相比,以及综合组与对照组治疗后相比,T淋巴细胞亚群差异有显著性意义(P＜0.05).结论:对恶性肿瘤患者放疗时加用康艾注射液能提高疗效,减轻副作用.

Treating 57 Cases of Malignant Tumor by Kangai Injection and Radiotherapy

Objective: To explore the function of increasing the therapeutic effect and releasing the toxic of Kangai injection combined with radiotherapy on treating malignant tumor.Methods: 110 cases with malignant tumor were randomly divided into the integration group and the contrast group.6MW-X ray produced by accelerator with conventionally field and conventionally-fractionated(CF) was adopt during radiotherapy.Cases with cervix cancer were given by outer irradiation and end irradiation.The integration group was treated by kanga injection for 40 days after radiotherapy and the contrast group was treated by radiotherapy only.Results: The catabatic ratios of controlled tumor in the integration group and the contrast group were 66.7% and 43.4% respectively.The improvement ratios of karnofsky grade were 52.6% and 32.1% respectively.The occurrence ratios of leucocyte decrease were 22.8% and 42.5% respectively.All difference had significant meaning(P<0.05).About T lymphocyte subtype,there was no significant difference in the integration group before and after therapy(P>0.05),while there was significant difference in the contrast group before and after therapy(P<0.05).Compared with the integrated group and the contrast group,there also had significant differentce(P<0.05).Conclusion: Kangai injection can improve the curative effect and lighten the side effect of radiotherapy on treating malignant tumor.