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人与猪肝门静脉几何形态学的比较研究
引用本文:张一飞 王配军 李文春 孙万群 黄铁柱. 人与猪肝门静脉几何形态学的比较研究[J]. 郧阳医学院学报, 2004, 23(1): 9-11,F003
作者姓名:张一飞 王配军 李文春 孙万群 黄铁柱
作者单位:郧阳医学院解剖教研室 湖北十堰442000(张一飞,王配军,李文春,孙万群),郧阳医学院解剖教研室 湖北十堰442000(黄铁柱)
基金项目:湖北省教育厅基金资助项目 (No2 0 0 3z0 0 1)
摘    要:目的 :比较研究人与猪肝门静脉的几何形态学指标间的异同 ,为猪→人异种肝移植提供形态学资料。方法 :取人与不同月龄猪肝门静脉 ,常规石蜡包埋、切片 ,HE染组织结构 ,光镜观察 ,计算机图像分析系统测定其几何形态学指标。结果 :猪与人肝门静脉壁的组织学结构类似 ,猪肝门静脉的管径、壁厚、管腔面积、管壁面积均随月龄的增长而增长 ,与月龄均呈直线正相关关系。 6月龄猪肝门静脉的形态学指标与人相近。结论 :猪肝门静脉的几何形态学指标随增龄发生变化 ,6月龄猪肝门静脉的管径、壁厚、管腔面积、管壁面积与人相近。

关 键 词:  肝门静脉  形态学  异种移植
文章编号:1006-9674(2004)01-009-03
修稿时间:2003-11-23

The comparative study on morphological differences of the hepatic portal vein between human beings and pigs
ZHANG Yi-fei,WANG Pei-jun,LI Wen-chun,et al.. The comparative study on morphological differences of the hepatic portal vein between human beings and pigs[J]. Journal of Yunyang Medical College, 2004, 23(1): 9-11,F003
Authors:ZHANG Yi-fei  WANG Pei-jun  LI Wen-chun  et al.
Abstract:Objective To compare the morphological difference of the hepatic portal vein between human beings and pigs and provide essential morphological data for pig-to-human liver xenotransplantation.Methods The hepatic portal vein of human beings and pigs were collected and diameter,wall thickness,luminal area,cross-sectional area were measured with image analysis system at light microscopic level.Results There was a linear relationship of the pig vessels diameter,wall thickness,luminal area, cross-sectional area and age increase. There was no difference between the 6 month-old pigs and normal adult humans.Conclusion The geometrical morphological data of porcine hepatic portal vein changed with aging,the diameter,wall thickness,luminal area,cross-sectional area of 6 month-old pig was similar to that in human beings.
Keywords:Pig  Hepatic portal vein  Morphology  Xenotransplantation
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