两种体外照射方法治疗宫颈癌不良反应分析

目的: 通过观察2种体外照射在宫颈癌放疗中的不良反应,获取宫颈癌最佳的放疗方案.方法: 随机将60例Ⅱb期以上宫颈癌患者分为观察组和对照组各30例,观察组采用同中心体外照射,每周 5 次,每日每野肿瘤量(DT)1.0 Gy,每日照射两野;对照组采用盆腔前后野对穿体外照射,每周5次,每日每野 DT 1.8～2.0 Gy,每日两野轮流照射,盆腔外照射DT 50 Gy,腔内后装治疗3～7次,每周1次,每次A点 DT 6.0～7.0 Gy.比较2组患者因放疗引起的骨髓抑制和消化系统反应发生情况.结果: 观察组患者放疗引起的消化系统反应程度轻于对照组(P< 0.05).2组骨髓抑制程度差异无统计学意义(P >0.05).结论: 在宫颈癌放疗中,采用同中心体外照射可相对减轻不良反应.

Analysis of adverse reactions of two kinds of external radiotherapy in cervical cancer

Objective: To observe the adverse reactions of two kinds of external radiotherapy in cervical cancer,and provide the best therapeutic method.Methods: Sixty patients with stage B or worse cervical cancer were randomly divided into observation group and control group with 30 cases in each group,the observation group with the same center of external irradiation,5 times a week,every day and every wild tumor volume(DT) 1.0 Gy, daily exposure to two wild;the control group before and after wear on the field by pelvic irradiation in vitro, 5 times every week,every day and wild DT 1.8-2.0 Gy, daily two wild turns irradiation,pelvic external irradiation of DT 50 Gy,intracavitary brachy therapy for 3-7 times, once a week, each time DT for 6.0-7.0 Gy.The incidence of bone marrow suppression and digestive system reaction induced by radiotherapy were compared between the 2 groups.Results: The digestive system of reaction degree caused by radiotherapy group less than that in the control group(P< 0.05),the 2 groups had no significant differences in the degree of suppression of bone marrow(P>0.05). Conclusions: In cervical cancer,using in vitro irradiation with center can relatively reduce adverse reactions.