1. Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, MD 20014, U.S.A.;2. Pediatric Metabolism Branch, National Institute of Arthritis, Metabolism, and Digestive Diseases, Bethesda, MD 20014 U.S.A.
Abstract:
Young adults with cystic fibrosis in good to excellent condition have reduced plasma sodium and chloride and elevated plasma potassium compared to a group of healthy young adult control subjects. Blood pressure was also lower in the patients with cystic fibrosis. However, plasma norepinephrine and dopamine-beta-hydroxylase and their response to standing and isometric hand grip were normal in the cystic fibrosis patients.