| 大豆异黄酮对小鼠实验性肝损伤的保护作用 |
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| 引用本文： | 曾靖,刘春棋,江丽霞,叶和杨. 大豆异黄酮对小鼠实验性肝损伤的保护作用[J]. 时珍国医国药, 2005, 16(10): 989-990 |
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| 作者姓名： | 曾靖 刘春棋 江丽霞 叶和杨 |
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| 作者单位： | 1. 赣南医学院,江西,赣州,341000
2. 赣南医学院附属医院,江西,赣州,341000 |
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| 摘 要： | 目的：探讨大豆异黄酮对小鼠实验性肝损伤的保护作用。方法：采用四氯化碳（CCl4）、硫代乙酰胺（TAA）、扑热息痛（AAP）致小鼠急性肝损伤模型，测定小鼠血清SGPT活性。结果：大豆异黄酮对四氯化碳、扑热息痛致小鼠实验性肝损伤有明显保护作用。大豆异黄酮对硫代乙酰胺所致小鼠实验性肝损伤无明显的保护作用。结论：大豆异黄酮可明显降低四氯化碳、扑热息痛致小鼠急性肝损伤模型血清SGPT活性。而对硫代乙酰胺致小鼠急性肝损伤模型血清SGPT活性无明显作用。
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| 关 键 词： | 大豆异黄酮 肝损伤 谷丙转氨酶 |
| 文章编号： | 1008-0805（2005）10-0989-02 |
| 收稿时间： | 2005-01-10 |
| 修稿时间： | 2005-06-12 |
Protective Effects of Soybean Isoflavones on Experimental Hepatic Injuries |
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| ZENG Jing,LIU Chun-qi,JIANG Li-xia,YE He-yang. Protective Effects of Soybean Isoflavones on Experimental Hepatic Injuries[J]. Lishizhen Medicine and Materia Medica Research, 2005, 16(10): 989-990 |
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| Authors: | ZENG Jing LIU Chun-qi JIANG Li-xia YE He-yang |
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| Affiliation: | 1. Department of Pharmacology, Gannan Medical College ,Ganzhou, Jiangxi 341000, China; 2. Affiliated Hospital of Gannan Medical College, Ganzhou, Jiangxi 341000, China |
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| Abstract: | Objective:To study the protective effect of soybean isoflaveones on experimental hepatic injuries.Methods:The activity of serum SGPT were measured in the model mice of hepatic injury induced by carbon tetrachloride(CCl_4),Acetaminophen(AAP) and Thioacetamide(TAA).Results:The serum SGPT activity was significantly lowered in the model mice of hepatic injuries induced by CCl_4,AAP and TAA after soybean isoflavones was given orally.Conclusion:Soybean isoflavones exhibited protective effect on experimental hepatic injuries. |
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| Keywords: | Soybean isoflavonesl Hepatic injury SGPT |
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