| 急性髓性白血病FLT3检测及临床意义 |
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| 引用本文： | 庞丽萍,张文丽,冯佳,徐海婵,许蕾,张倩,孙丽华,孟庆祥. 急性髓性白血病FLT3检测及临床意义[J]. 罕少疾病杂志, 2011, 18(1): 7-9. DOI: 10.3969/j.issn.1009-3257.2011.01.002 |
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| 作者姓名： | 庞丽萍 张文丽 冯佳 徐海婵 许蕾 张倩 孙丽华 孟庆祥 |
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| 作者单位： | 北京大学深圳医院血液科,广东,深圳,518036 |
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| 摘 要： | 目的 探讨FLT3在急性髓性白血病(AML)中的表达情况.方法 核型正常的AML患者20例,核型异常的AML患者30例,分别于化疗前抽取骨髓3ml,用PCR方法检测白血病细胞FLT3的表达情况.结果 核型正常的AML FLT3的表达率为5.0%,核型异常的AML FLT3的表达率为26.7%.难治复发的AML FLT3...
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| 关 键 词： | 临床意义 FLT3 AML |
The diction and clinical significance of fms-related tyrosine Kinase 3(FLT3) in acute myeloid leukemia |
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| PANG Li-ping,ZHANG Wen-li,FNEG Jia,XU Hai-chan,XU Lei,ZHANG Qian,SUN Li-hua,MENG Qing-xiang. The diction and clinical significance of fms-related tyrosine Kinase 3(FLT3) in acute myeloid leukemia[J]. Journal of Rare and Uncommon Diseases, 2011, 18(1): 7-9. DOI: 10.3969/j.issn.1009-3257.2011.01.002 |
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| Authors: | PANG Li-ping ZHANG Wen-li FNEG Jia XU Hai-chan XU Lei ZHANG Qian SUN Li-hua MENG Qing-xiang |
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| Affiliation: | PANG Li-ping,ZHANG Wen-li,XU Lei,FNEG Jja,ZHANG Qian,LI Zi-jun,SUN Li-hua,MENG Qing-xiang,Department of Hematology,Beijing University Shen Zhen Hospital,Shen Zhen 518036,China |
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| Abstract: | Objective To explore the expression of fms-related tyrosine Kinase 3(FLT3) in acute myeloid leukemia(AML).Methods AML patients with normal karyotype were 20 cases,the abnormal karyotype were 30 cases.Aspiration bone marrow 3ml before themotherapy respectively,to detect the FLT3 expression in leukemia cells with polyenzyme chain react(PCR).Results The FLT3 expression rate in AML patients with normal karyotype is 5.0%,and 26.7% is in AML Patients with abnormal karyotype,and 33.3% is in AML patients with refra... |
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| Keywords: | Clinical Significance FLT3 AML |
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