乳晕真皮内注射蓝色染料法前哨淋巴结活检的应用

目的 探讨使用乳晕真皮内注射蓝色染料法前哨淋巴结活检在早期乳腺癌治疗中的作用和价值。方法 回顾性分析25例早期乳腺癌患者应用乳晕真皮内注射蓝色染料法前哨淋巴结活检的临床结果。结果 25例患者中成功检测出前哨淋巴结者24例,检出率为96．0％。共检出前哨淋巴结62枚,平均每例2．5枚。病理结果中HE染色5例淋巴结有转移,免疫组化染色7例阳性。本组前哨淋巴结检出的灵敏度为87．5％;准确性96．0％;假阴性率12．5％;假阳性率0。结论 应用乳晕真皮内注射蓝色染料法前哨淋巴结活检在早期乳腺癌治疗中同样可以取得较高的检出率和准确性。

Application of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of breast carcinoma

Objective To probe into the feasibility and accuracy of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early stage breast carcinoma. Methods Retrospective analysis of 25 cases of early stage breast cancer who were carried out subareolar injection of blue dye method for sentinel lymph node biopsy. Results Of 25 cases, 24 were checked out sentinel lymph nodes. Check out rate was 96 0%. Totally 62 sentinel lymph nodes were checked out, each patient had 2 5 nodes averagely. There were 5 cases with lymph node metastases in HE stain, and 7 cases with positive nodes in IHC stain. Sensitivity in this group was 87 5%; Accuracy 96 0%; False negative rate 12 5%; False positive rate 0. Conclusion Application of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early stage breast carcinoma can also acquire high check out rate and high accuracy.