鼻咽癌放疗后复发转移39例临床分析

目的探讨鼻咽癌放疗后复发或转移的临床特征及其危险因素。方法回顾性分析我院39例鼻咽癌患者放疗后复发或转移的部位、时间、TNM分期、治疗方式等。结果局部复发或转移多在24月内，T分期为局部复发的危险因素，临床分期为远处转移的危险因素。腔内治疗、化学治疗对T2期、早期患者有益。结论鼻咽癌患者随访时应注意无症状的转移灶的发现。腔内照射和化学治疗对早期患者能改善预后。

Clinical analysis of 39 cases of recurrence or metastasis of nasopharyngeal carcinoma after radiotherapy

Objective To discuss the clinical characteristics and risk factors of recurrent or metastasized nasopharyngeal carcinoma after radiotherapy.Methods Thirty-nine cases of recurrent or metastasized nasopharyngeal carcinoma after radiotherapy were analyzed in terms of the metastasized site and time,TNM stage and treatment protocols.Results Local recurrence or metastasis of the nasopharyngeal carcinoma usually happened within 24 months.TNM stage exhibited the high risk tendency for local recurrence and the clinical stage revealed the high risk tendency for distal metastasis as well.Intra-cavity radiotherapy or chemotherapy was beneficial for patients with early stage nasopharyngeal cancer.Conclusion Meticulous measures have to be taken to find the asymptomatic metastasized focus at early time.Intra-cavity radiotherapy or chemotherapy will ameliorate prognosis of patients with early stage nasopharyngeal cancer.