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| 恰玛古蜜膏对小鼠免疫功能的影响 | |
| 引用本文： | 孙艳,安熙强,马媛,张涛,姚华,贾鸿雁,张亚辉. 恰玛古蜜膏对小鼠免疫功能的影响[J]. 中国医药导报, 2010, 7(6): 20-22 |
| 作者姓名： | 孙艳 安熙强 马媛 张涛 姚华 贾鸿雁 张亚辉 |
| 作者单位： | 1. 石河子大学药学院,新疆石河子,832000 2. 新疆维吾尔自治区药物研究所,新疆乌鲁木齐,830004 3. 新疆柯坪圣泉实业有限公司,新疆乌鲁木齐,830000 |
| 基金项目： | 新疆维吾尔自治区重点实验室项目 |
| 摘 要： | 目的：研究恰玛古蜜膏对小鼠免疫功能的影响。方法：通过紫外分光光度法测定小鼠单核-巨噬细胞对血流中碳粒的清除能力及小鼠血清中IgM抗体水平;测定小鼠耳廓肿胀度,观察恰玛古蜜膏对二硝基氯苯诱导的小鼠迟发型超敏反应的影响;镜检计数观察小鼠腹腔巨噬细胞吞噬鸡红细胞的能力。结果：恰玛古蜜膏40g/kg剂量能明显提高小鼠单核-巨噬细胞对血流中碳粒的清除能力,促进小鼠血清中IgM抗体的生成,提高小鼠腹腔巨噬细胞吞噬鸡红细胞的能力;恰玛古蜜膏40g/kg剂量和20g/kg剂量能明显增强二硝基氯苯诱导的小鼠迟发型超敏反应。结论：恰玛古蜜膏可增强机体的免疫功能。 |
| 关 键 词： | 恰玛古 小鼠 免疫调节 |
The effect of Brassica Campestris Ointment on immune function of mice |
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| SUN Yan,AN Xiqiang,MA Yuan,ZHANG Tao,YAO Hua,JIA Hongyan,ZHANG Yahui. The effect of Brassica Campestris Ointment on immune function of mice[J]. China Medical Herald, 2010, 7(6): 20-22 | |
| Authors: | SUN Yan AN Xiqiang MA Yuan ZHANG Tao YAO Hua JIA Hongyan ZHANG Yahui |
| Affiliation: | 1.School of Pharmacy, Shihezi University, Shihezi 832000, China; 2.Institute of Meteria Medica, Xinjiang Uygur Autonomous Region, Urumqi 830004, China; 3.The Company of Health Products of Keping Shengquan, Urumqi 830000, China) |
| Abstract: | Objective：To study the effect of Brassica Campestris Ointment on immune function of mice. Methods：The influence of Brassica Campestris Ointment on carbongranular clearance ability of mononuclear macrophage in mice and the IgM level were determined by ultraviolet spectrophotometry,tumefaction of ear was determined through the delayed type hypersensitivity （DTH） induced by DNCB; the ability of englobing red blood cells of chicken of peritoneal macrophage in mice was observed by microscopic examination. Results：Carbongranular clearance ability of mononuclear macrophage,the level of IgM and the ability of englobing red blood cells of chicken of peritoneal macrophage in mice were enhanced significantly by the 40 g/kg dosage group of Brassica Campestris Ointment; DTH induced by DNCB was enhanced significantly by the 40 g/kg dosage group and 20 g/kg dosage group of Brassica Campestris Ointment. Conclusion：Brassica Campestris Ointment has effect on improving the immunological function of mice. |
| Keywords: | Brassica campestris Mice Immune function |
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