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鼻咽癌放射性脑病的诊断和治疗
引用本文:仆俊国,袁亚维,石玉生. 鼻咽癌放射性脑病的诊断和治疗[J]. 南方医科大学学报, 2000, 20(1)
作者姓名:仆俊国  袁亚维  石玉生
作者单位:第一军医大学珠江医院放疗科!广东 广州510282,第一军医大学珠江医院放疗科!广东 广州510282,南方医院放疗科!广东广州510515
摘    要:目的分析鼻咽癌放射性脑病(REP)的诊断和治疗方法。材料和方法为28例鼻咽癌放疗后放射性脑病患者行CT检查,其中10例又行MRI检查,9例在我院接受治疗。结果和结论(1)CT对鼻咽癌放射性脑病的诊断有一定价值,但MRI对后颅窝和脑干病变的显示优于CT;(2)放射性脑病可能是放疗致脑组织血管损伤后引起免疫改变的结果:(3)本组9例患者经应用激素、甘露醇、多种维生素等治疗,均取得不同程度的改善。因此.建议对鼻咽癌放疗后放射性脑病积极尽快治疗。

关 键 词:鼻咽癌  放射性脑病  诊断  治疗

Diagnosis and therapy of radiation encephalopathy after radiotherapy for nasopharyngeal cacinoma
BU Jun-guo,YUAN Ya-wei,SHI Yu-sheng. Diagnosis and therapy of radiation encephalopathy after radiotherapy for nasopharyngeal cacinoma[J]. Journal of Southern Medical University, 2000, 20(1)
Authors:BU Jun-guo  YUAN Ya-wei  SHI Yu-sheng
Affiliation:BU Jun-guo,YUAN Ya-wei,SHI Yu-sheng Department of Radiotherapy,Zhujiang Hospital,Guangzhou 510282,China,Nanfang Hospital,First Military Medical University,Guangzhou 510515,China
Abstract:Objective To evaluate the methods for the diagnosis and therapy of radiation encephalopathy (REP) after radiotherapy for nasopharyngeal cacinoma (NPC). Materials and methods 28 patients with REP due to radiotherapy for NPC were examined with CT. Among whom 10 were also examined with MRI. and 9 were treated in our hospital, Results and conclusions (1) MRI is better than CT to show the lesion of cerebellar fossa and brain stem.(2) REP may be resulted from immunal resonse to the damage of brain tissue and blood vessel after radiotherapy, (3) To some degree the symptoms of the 9 patients were alleviated ailer therapy With dexamethasome, mannital and vitamine B, etc. REP ought to he treated vigorously as soon as possible.
Keywords:nasopharyngeal cacinoma  radiation encephalopathy  diagnosis  therapy
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