| 益肾中药复方防治大鼠继发性骨质疏松症的实验研究 |
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| 引用本文： | 王育才,丁勇,范清宇,张殿忠,单乐群,尹艳.益肾中药复方防治大鼠继发性骨质疏松症的实验研究[J].第四军医大学学报,2009,30(11):1001-1003. |
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| 作者姓名： | 王育才 丁勇 范清宇 张殿忠 单乐群 尹艳 |
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| 作者单位： | 第四军医大学唐都医院骨科,陕西,西安,710038
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| 摘 要： | 目的：益肾中药复方用于实验性继发性骨质疏松症模型大鼠，观察其疗效，并对中药复方的机制做初步的探讨．方法：使用糖皮质激素肌肉注射制造继发性骨质疏松症动物模型，同时给予益肾中药复方治疗3mo后，观察模型动物股骨骨密度（BMD）、血钙、血磷、血碱性磷酸酶（AKP）理化指标．结果：益肾中药复方治疗组大鼠股骨BMD高于模型组（P〈0．05），血钙、血磷、血AKP等均高于模型组（P〈0．05）．结论：益肾中药复方能在一定程度上缓解由糖皮质激素诱发的骨质疏松症．
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| 关 键 词： | 骨质疏桫病因学 中药复方 大鼠 |
Treatment and protection of secondary osteoporosis in rats with Kidney-Tonifying Chinese herb compound |
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| WANG Yu-Cai,DING Yong,FAN Qin-Yu,ZHANG Dian-Zhong,SHAN Le-Qun,YIN Yan.Treatment and protection of secondary osteoporosis in rats with Kidney-Tonifying Chinese herb compound[J].Journal of the Fourth Military Medical University,2009,30(11):1001-1003. |
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| Authors: | WANG Yu-Cai DING Yong FAN Qin-Yu ZHANG Dian-Zhong SHAN Le-Qun YIN Yan |
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| Institution: | WANG Yu-Cai,DING Yong,FAN Qin-Yu,ZHANG Dian-Zhong,SHAN Le-Qun,YIN Yan Department of Orthopedic Surgery,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China |
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| Abstract: | AIM:To observe the effect of Kidney-Tonifying Chinese herb compound on rats with secondary osteoporosis and to explore its mechanism.METHODS:By intramuscular injection of dexamethasone,the animal model of secondary osteoporosis was made and the animals were then given Kidney-Tonifying Chinese herb compound for 3 months.Bone mineral density(BMD) of femur and serum Ca,P and AKP were determined.RESULTS:The BMD of femur and the values of serum Ca,P and AKP in Chinese herb compound group were higher than those i... |
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| Keywords: | osteoporosis/ET Chinese herb compounds rats |
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