Evaluation of the Effect of Routine Antibiotic Administration after Uterine Artery Embolization on Infection Rates |
| |
| Affiliation: | 1. Department of Vascular and Interventional Radiology, Christiana Care Health System, 4755 Ogletown Stanton Rd, Ste 1e20, Newark, DE 19713;2. Radiology Group of Abington, Abington Hospital–Jefferson Health, Abington, Pennsylvania;3. Department of Radiology, Christiana Care Health System, 4755 Ogletown Stanton Rd, Ste 1e20, Newark, DE 19713;2. Department of Intervention Medicine, the Second Hospital of Shandong University, 247 Beiyuan Road, Jinan 250033, Shandong, People’s Republic of China;1. Department of Intervention Medicine, the First Hospital of Nanping Affiliated to Fujian Medical University, Nanping, Fujian, China;3. Interventional Oncology Institute of Shandong University, Jinan, Shandong, People’s Republic of China;4. Department of Radiology, Ben Gurion University of the Negev, Beersheba, Israel;1. Department of Vascular Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, China;2. Vascular Center of Shanghai Jiao Tong University, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, China;1. Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322;2. Department of Internal Medicine, Kennestone Hospital, Wellstar, Atlanta, Georgia;3. Department of Radiology, Capital Regional Medical Center, Tallahassee, Florida;1. Department of Vascular and Interventional Radiology, Saint Louis University, 3635 Vista Ave., St. Louis, MO, 63110;2. Department of Radiology, Saint Louis University, 3635 Vista Ave., St. Louis, MO, 63110;3. Saint Louis University Center for Health Outcomes Research, Saint Louis University, 3635 Vista Ave., St. Louis, MO, 63110;4. School of Medicine, Saint Louis University, 3635 Vista Ave., St. Louis, MO, 63110 |
| |
| Abstract: | PurposeTo evaluate the effect of routine administration of post-procedural antibiotics following elective uterine artery embolization (UAE) on infectious complication rates.Materials and MethodsThe charts of patients who underwent UAE between January 2013 and September 2019 were retrospectively reviewed. Prior to January 15, 2016, all patients received post-procedural antibiotics with 500 mg of ciprofloxacin twice a day orally for 5 days. After January 15, 2016, none of the patients received post-procedural antibiotics. All patients in both groups received pre-procedural intravenous antibiotics. The post-procedural antibiotics group included 217 patients (age, 44.7 ± 6 years); the no-antibiotics group included 158 patients (age, 45.4 ± 5.6 years). Patients in the no-antibiotics group had a significantly higher rate of diabetes mellitus (P = .03) but fewer cases of adenomyosis (P = .048). Otherwise, demographic and fibroid characteristics were similar between the groups.ResultsSix infectious complications (6/375, 1.6%) were recorded. No statistically significant difference (P = .66) was observed in the number of infections between the post-procedural antibiotics group (4/217, 1.8%) and the no-antibiotics group (2/158, 1.3%). Three of the 6 infectious complications presented with malodorous vaginal discharge (3/375, 0.8%) and received nominal therapy. The 3 remaining complications (0.8%) were considered major and included 2 patients (0.5%) who underwent hysterectomy and 1 patient (0.3%) who underwent myomectomy. The major infection rate was 0.9% (2/217) in the post-procedural antibiotics group and 0.7% (1/158) in the no-antibiotics group (P = 1). There were no 90-day post-procedural mortalities.ConclusionsDiscontinuation of routine post-procedural antibiotics with ciprofloxacin after elective UAE did not result in increased rates of infectious complications within the first 90 days post procedure. |
| |
| Keywords: | FIBROID" },{" #name" :" keyword" ," $" :{" id" :" kwrd0015" }," $$" :[{" #name" :" text" ," _" :" Fibroid Registry for Outcomes Data HOPEFUL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0025" }," $$" :[{" #name" :" text" ," _" :" Hysterectomy Or Percutaneous Embolisation For Uterine Leiomyoma UAE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" uterine artery embolization |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
