Yttrium-90 Radioembolization for Hepatocellular Carcinoma with Portal Vein Invasion: Validation of the Milan Prognostic Score期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

按检索

Yttrium-90 Radioembolization for Hepatocellular Carcinoma with Portal Vein Invasion: Validation of the Milan Prognostic Score

Institution:	1. Department of Interventional Radiology, Pisa University Hospital, via Paradisa 2, 56100 Pisa, Italy;2. Department of Nuclear Medicine, Pisa University Hospital, via Paradisa 2, 56100 Pisa, Italy;3. Department of Health Physics, Pisa University Hospital, via Paradisa 2, 56100 Pisa, Italy;1. The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland;2. Massachusetts General Hospital, Boston, Massachusetts;1. Department of Neurology, Christchurch Hospital, Private Bag 4710, Christchurch 8140, New Zealand;2. Department of Interventional Radiology, Christchurch Hospital, Private Bag 4710, Christchurch 8140, New Zealand;3. Central Oregon Radiology Associates, Bend, Oregon;4. New Zealand Brain Research Institute, Christchurch, New Zealand;1. Department of Vascular Surgery, University Hospital Aachen, Pauwelsstrasse 30, Aachen 52074, Germany;2. Clinic for Diagnostic and Interventional Radiology/Nuclear Medicine, Clinical Center of Friedrichshafen, Friedrichshafen, Germany;3. Department of Cardiovascular Surgery, University of Health Sciences, Ankara, Turkey;4. Heart and Vascular Center, St. Joseph Hospital, Orange, California;1. Department of Diagnostic and Interventional Radiology, RWTH Aachen University Hospital, Aachen, Germany;2. Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University, Aachen, Germany;3. Department of Radiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan;1. Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., 1 Founders, MRI Education Center, Philadelphia, PA 19104;2. Environmental Health and Radiation Safety, University of Pennsylvania, Philadelphia, Pennsylvania;3. Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania;1. Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan;2. Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan;3. Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Hyogo, Japan

Abstract:	The aim of the present study was to retrospectively analyze clinical outcomes of patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) treated with yttrium-90 radioembolization stratified by Milan PVTT score according to PVTT extension, tumor burden, and bilirubin levels. Seventy patients were included and classified into good (n = 15; 21.4%), intermediate (n = 33; 47.1%), and dismal (n = 22; 31.4%) prognostic groups. Median overall survival durations were 24.6 mo, 13 mo (hazard ratio = 3.2; 95% confidence interval CI], 1.2–9.7; P = .016), and 5.9 mo (hazard ratio = 4.1; 95% CI, 1.4–13.4; P = .0096), respectively. The Milan score represents an easy tool to select patients with HCC with PVTT who may benefit from radioembolization.

Keywords:	CI"} {"#name":"keyword" "$":{"id":"kwrd0015"} "$$":[{"#name":"text" "_":"confidence interval HCC"} {"#name":"keyword" "$":{"id":"kwrd0025"} "$$":[{"#name":"text" "_":"hepatocellular carcinoma IQR"} {"#name":"keyword" "$":{"id":"kwrd0035"} "$$":[{"#name":"text" "_":"interquartile range OS"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"overall survival PD"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"progressive disease PVTT"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"portal vein tumor thrombosis
本文献已被 ScienceDirect 等数据库收录！

设为首页 | 免责声明 | 关于勤云 | 加入收藏