Factors Affecting Recurrent Deep Vein Thrombosis after Pharmacomechanical Thrombolysis and Left Iliac Vein Stent Placement in Patients with Iliac Vein Compression Syndrome |
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| Institution: | 1. Department of Radiology, Jeonbuk National University Medical School and Hospital, Jeonju, Jeonbuk, Republic of Korea;2. Department of Surgery, Jeonbuk National University Medical School and Hospital, Jeonju, Jeonbuk, Republic of Korea;3. Research Institute of Clinical Medicine, Jeonbuk National University Biomedical Research Institute of Jeonbuk, National University Hospital, Jeonbuk, Republic of Korea;1. Department of Vascular Surgery, Zhongshan Hospital, Affiliated to Fudan University, Shanghai, People''s Republic of China;2. Department of Vascular Surgery, Qingpu Branch of Zhongshan Hospital, Affiliated to Fudan University, Shanghai, People''s Republic of China;1. Image-Guided Therapy Center, Department of Vascular and Interventional Radiology, Hôpital Universitaire François-Mitterrand, 14, rue Paul-Gaffarel, BP 77908, 21079 Dijon cedex, France;2. Department of Angiology and Vascular Medicine, Hôpital Universitaire François-Mitterrand, 21079 Dijon, France;3. Department of Epidemiology, Statistics and Clinical Research, Hôpital Universitaire François-Mitterrand, 21079 Dijon, France;4. Department of Biological Hemostasis and Thrombosis Treatment, Hôpital Universitaire François-Mitterrand, 21079 Dijon, France;5. Department of Internal Medicine and Clinical Immunology, Hôpital Universitaire François-Mitterrand, 21079 Dijon, France |
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| Abstract: | PurposeThis study evaluated the factors affecting contralateral and ipsilateral recurrent deep vein thrombosis (DVT) after iliac vein stent placement in patients with iliac vein compression syndrome (IVCS).Materials and MethodsData from 130 patients (95 female patients) who underwent catheter-directed thrombolysis and stent placement for IVCS with left lower leg thrombosis at a single institution were retrospectively analyzed. Mean patient age was 69.0 ± 14.0 years old. Median follow-up was 14 months (range, 3–164 months). Anticoagulation therapy was prescribed for 6 months, followed by lifelong antiplatelet therapy. Multivariate logistic regression analysis was performed to evaluate the factors affecting the development of contralateral and ipsilateral recurrent DVT.ResultsSeven patients (5.4%) developed contralateral DVT (median, 26 months; range, 2–61 months), and 11 patients (8.5%) developed ipsilateral DVT (median, 1 month; range, 0–53 months). Stent location (odds ratio OR], 11.564; 95% confidence interval CI], 1.159–115.417) and in-stent thrombosis during follow-up (OR, 15.142; 95% CI, 1.406–163.119) were predictors of recurrent contralateral DVT. Thrombophilia (OR, 47.560; 95% CI, 2.369–954.711), remaining inferior vena cava filter (OR, 30.552; 95% CI, 3.495–267.122), and in-stent thrombosis during follow-up (OR, 82.057; 95% CI, 2.915–2309.848) were predictors of ipsilateral DVT.ConclusionsContralateral DVT occurs late and is associated with extension of the iliac vein stent to the inferior vena cava and in-stent thrombosis. Ipsilateral DVT occurs relatively early and is associated with thrombophilia, remaining inferior vena cava filter, and in-stent thrombosis. |
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| Keywords: | CIV"} {"#name":"keyword" "$":{"id":"kwrd0015"} "$$":[{"#name":"text" "_":"common iliac vein DUS"} {"#name":"keyword" "$":{"id":"kwrd0025"} "$$":[{"#name":"text" "_":"Doppler ultrasonography DVT"} {"#name":"keyword" "$":{"id":"kwrd0035"} "$$":[{"#name":"text" "_":"deep vein thrombosis IVCS"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"iliac vein compression syndrome VIH"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"venous intimal hyperplasia |
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