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Factors Influencing in-Stent Occlusion after Femoropopliteal Artery Stent Placement with Intravascular Ultrasound Evaluation
Institution:1. Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;2. Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;3. Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;4. Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;5. Department of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany;1. Duke University School of Medicine, Durham, North Carolina 27710;2. Vascular and Interventional Specialists, Charlotte Radiology, Charlotte, North Carolina;3. Department of Radiology, Division of Interventional Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland;4. Department of Radiology, Division of Interventional Radiology, Duke University Medical Center, 2301 Erwin Road, Box 3808, Durham, NC;1. Department of Radiology, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, 443-749, Suwon, Korea;2. Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, 443-749, Suwon, Korea;1. Department of Pediatric Radiology, Diagnostic Imaging, McMaster Children’s Hospital, 1200 Main St. W., Hamilton, ON L8N 3Z5, Canada;2. Division of Image Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada;1. Department of Radiology, Division of Interventional Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., 1 Silverstein, Philadelphia, PA 19104;2. Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania;1. Department of Vascular Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China;2. Department of Vascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China;3. Department of Vascular Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
Abstract:PurposeTo investigate the rate and predictors of in-stent occlusion by intravascular ultrasound (IVUS) following femoropopliteal artery stent placement.Materials and MethodsFrom July 2012 to June 2016, this study retrospectively investigated 191 cases of de novo femoropopliteal artery lesions (lesion length, 170 ± 97 mm; chronic total occlusion, 51%) evaluated by IVUS in 162 patients with peripheral artery disease (with critical limb ischemia of 27%) who underwent endovascular therapy using self-expanding nitinol stents. Examination by IVUS was performed to record data for vessel characteristics immediately after wire crossing and at the end of the procedure. The primary outcome measurement was the occurrence of in-stent occlusion, defined as the absence of blood flow at the treatment site by duplex ultrasonography. Predictors for in-stent occlusion were also evaluated by multivariate analysis.ResultsIn-stent occlusion was observed in 15% (n = 28) of lesions, and the mean follow-up time was 19 ± 13 months. After multivariate analysis, it was found that plaque burden ≥60% after stent placement (P < .001), female gender (P = .002), and Trans-Atlantic Inter-Society Consensus (TASC) II classification C and D lesions (P = .047) were significantly associated with the occurrence of in-stent occlusion.ConclusionsPlaque burden ≥60% after stent placement, female gender, and TASC II classification C/D lesions were significantly associated with the occurrence of in-stent occlusion after femoropopliteal artery stent placement as evaluated by IVUS.
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