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Efficacy and Safety of Ultrasound-Guided Supraclavicular Brachial Plexus Block during Angioplasty of Dysfunctional Arteriovenous Access: A Prospective,Randomized Single-Center Clinical Trial
Institution:1. Department of Radiology, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, 443-749, Suwon, Korea;2. Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, 443-749, Suwon, Korea;1. Duke University School of Medicine, Durham, North Carolina 27710;2. Vascular and Interventional Specialists, Charlotte Radiology, Charlotte, North Carolina;3. Department of Radiology, Division of Interventional Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland;4. Department of Radiology, Division of Interventional Radiology, Duke University Medical Center, 2301 Erwin Road, Box 3808, Durham, NC;1. Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;2. Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;3. Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;4. Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114;5. Department of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany;1. Department of Radiology, Instituto de Radiologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil;2. Department of Endocrinology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil;3. Endocrinology Unit, Instituto do Câncer do Estado de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, s/n˚ - Rua 1 – Cerqueira César, 05403-900, São Paulo, SP, Brazil;4. Department of Oncology, Instituto do Câncer do Estado de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, s/n˚ - Rua 1 – Cerqueira César, 05403-900, São Paulo, SP, Brazil;5. Instituto do Câncer do Estado de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, s/n˚ - Rua 1 – Cerqueira César, 05403-900, São Paulo, SP, Brazil;6. Interventional Radiology Unit, Rede de Hospitais São Camilo de São Paulo, São Paulo, SP, Brazil;7. Neurophysiology Unit, Rede de Hospitais São Camilo de São Paulo, São Paulo, SP, Brazil
Abstract:PurposeTo evaluate the efficacy and safety of the ultrasound-guided supraclavicular brachial plexus block (BPB) during angioplasty of dysfunctional arteriovenous access.Materials and MethodsEighty study participants with dysfunctional arteriovenous access were enrolled in this prospective, randomized clinical trial between November 2016 and February 2018. Eighty patients were randomized to either the ultrasound-guided supraclavicular BPB group (mean age ± standard deviation SD], 65.1 ± 12.4; male:female = 17:23) or the no regional anesthesia group (mean age ± SD, 64.0 ± 11.7; male:female = 25:15). Pain was assessed on the 10-point Visual Analogue Scale. Participant satisfaction was examined. Six-month clinical follow-up was done to evaluate arteriovenous access patency and long-term complications.ResultsThe BPB group showed a lower average pain score than the control group (mean ± SD, 0.9 ± 1.9 vs 6.4 ± 2.5; P < .001). Participant satisfaction (mean ± SD, 2.8 ± 0.5 vs 2.1±0.8; P < .001) was also higher in the BPB group. Six-month patency was 65% (26/40) in the BPB group and 59% (23/39) in the control group, with no significant difference between the 2 groups (P = .59). No major immediate or delayed complications were observed.ConclusionsUltrasound-guided BPB is highly effective in reducing pain during angioplasty of dysfunctional arteriovenous access with an acceptable safety profile.
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