妊娠恶阻孕妇中医证型分布及精神心理状态分析

目的对妊娠恶阻孕妇的中医证型分布及精神心理状态进行统计分析,探究妊娠恶阻孕妇中医证型与焦虑抑郁的相关性。方法选取2017年3月—2018年3月期间符合纳入标准的妊娠恶阻孕妇114例为病例治疗组,再选取正常早期妊娠孕妇117例为对照组。所有受试者均填写一般情况调查表,随后填写焦虑自评量表(Self-Rating Anxiety Scale,SAS)和抑郁自评量表(Self-rating depression scale,SDS)并评分;治疗组再行中医证候分析确定其辨证分型,将两组受试者的一般情况和证型分布及焦虑抑郁情况进行汇总,统计分析其相关性。结果(1)治疗组受试者中肝胃不和型所占比例最大,其次为脾胃虚弱型,分别为34.21%和30.70%,再次为痰湿阻滞型占23.68%和气阴两虚型占11.40%。(2)治疗组受试者SAS和SDS评分均高于对照组(P<0.01)。(3)治疗组受试者中医证型与焦虑、抑郁存在一定的相关性(P<0.05),其中焦虑相关性更为明显(P<0.01)。结论妊娠恶阻孕妇中肝胃不和型所占比例最大,且焦虑、抑郁与中医证型存在一定相关性;妊娠恶阻会引起孕妇焦虑和抑郁,恶阻越重,焦虑、抑郁程度越高。

Analysis of TCM syndrome distribution and mental state of pregnant women with morning sickness

Objective To analyze the distribution of TCM syndromes and their mental state of pregnant women with morning sickness,and investigate the correlation between TCM syndromes and anxiety and depression.Methods A total of 114 cases of pregnant women with morning sickness who met the inclusion criteria were selected as the observation group,and 117 cases of normal early pregnant women were selected as the control group.All participants filled in general information form,then filled in the self-rating anxiety scale(SAS)and self-rating depression scale(SDS).The observation group was determined the results of syndrome differentiation.Then,the correlation of general condition,syndrome distribution and anxiety and depression condition were analyzed.Results 1.In the observation group,the syndrome of liver-stomach disharmony accounted for the largest proportion,followed by spleen-stomach weakness(34.21%and 30.70%respectively),and then the phlegm-dampness obstruction(23.68%)and qi and yin deficiency(11.40%).2.The SAS and SDS scores in the observation group were higher than those in the control group(P<0.01).3.There was a correlation between TCM syndrome and anxiety and depression in the observation group(P<0.05),and the correlation between anxiety was more significant(P<0.01).Conclusion The most common syndromes in pregnant women with morning sickness were liver-stomach disharmony,and there is a certain correlation between anxiety,depression and TCM syndrome.Morning sickness may lead to anxiety or depression in pregnant women,and the degree of morning sickness and the degree of anxiety and depression were positive correlated.