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Adverse Events Related to Partial Splenic Embolization for the Treatment of Hypersplenism: A Systematic Review
Affiliation:1. Department of Radiology, Section of Interventional Radiology, Northwestern University, Chicago, Illinois;2. Department of Medicine, Division of Hematology and Oncology, Northwestern University, Chicago, Illinois;1. Department of Radiology, San Raffaele Scientific Institute, Milan, Italy;2. Department of Vascular Surgery, San Raffaele Scientific Institute, Milan, Italy;3. Department of Radiology and Vascular Surgery, Vita-Salute San Raffaele University, Milan, Italy;1. Department of Radiology, Mayo Clinic, Rochester, Minnesota;2. Department of Urology, Mayo Clinic, Rochester, Minnesota;3. Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota
Abstract:Partial splenic embolization is a common procedure that reduces thrombocytopenia in patients with hypersplenism. The present review evaluated the adverse event profile of partial splenic embolization detailed in 30 articles. Although the technical success rate of the procedure in these papers is high, many patients experienced postprocedural complications. Minor complications such as postembolization syndrome occurred frequently. Major complications were less frequent but sometimes resulted in mortality. Underlying liver dysfunction and high infarction rates may be risk factors leading to major complications. Interventional radiologists should be aware of the complication profile of this procedure and further advance research in techniques dealing with hypersplenism.
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